Evidence map›Paper›PMID 40754756›Full record

Observational studyClinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery2025

Complications and Economic Burden of Surgery in Chronic Rhinosinusitis With Nasal Polyps: An Observational Cohort Study Using Swedish Register Data.

Petter Olsson, Christoph Abé, Maija Wolf, Mathias Lilja, Tina Maio-Twofoot, Ola Sunnergren, Pernilla Sahlstrand-Johnson

Abstract readObservational Study
In one paragraph

Observational study in Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Complications and Economic Burden of Surgery in Chronic Rhinosinusitis With Nasal Polyps: An Observational Cohort Study Using Swedish Register Data.Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery · 2025
    Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Petter OlssonDivision of Ear, Nose, and Throat Diseases, Department of Clinical Sciences, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden.ORCID 0000-0002-3913-3914
Christoph AbéQuantify Research, Stockholm, Sweden.ORCID 0000-0002-1680-8480
Maija WolfNovartis Finland, Espoo, Finland.ORCID 0009-0004-9046-8930
Mathias LiljaQuantify Research, Stockholm, Sweden.ORCID 0000-0001-7927-3770
Tina Maio-TwofootNovartis Pharma AG, Basel, Switzerland.
Ola SunnergrenDepartment of Otorhinolaryngology, Jönköping, Sweden.ORCID 0000-0002-1192-0182
Pernilla Sahlstrand-JohnsonDepartment of Otorhinolaryngology, Head and Neck Surgery, Skåne University Hospital, Lund University, Lund, Sweden.ORCID 0000-0001-5146-3636

Funding

Novartis Pharma AG, Basel, Switzerland
6 · The paper itself

Abstract

introductionThere is a lack of comprehensive data on complications following sinus surgery (SS) in patients with chronic rhinosinusitis with nasal polyps (CRSwNP). This study aimed to estimate the prevalence of SS-related complications in CRSwNP patients and examine patient characteristics, predictors of revision surgery, healthcare use, and associated costs using secondary care data from Swedish registers.

methodsThis observational cohort study used Swedish administrative register data to report patient characteristics and estimate the prevalence and incidence of SS-related complications among CRSwNP patients. Healthcare resource use (HCRU) and associated costs, the probability of and predictors for revision surgery were assessed.

resultsOut of 9178 CRSwNP patients who underwent SS, 8.5% experienced complications to SS. Asthma was the most frequently observed comorbidity. The probability of revision surgery within 4 years was 12%. Factors such as younger age at index, complications to first surgery, earlier index year, and comorbid asthma were significant predictors for future surgery. Within 4 years of follow-up, patients undergoing SS showed more HCRU and higher related costs compared to matched general population controls (€13 865 vs. €7088 per person; p < 0.001). Asthma comorbidity, the occurrence of complications, and undergone revision surgery were associated with higher costs.

conclusionOverall, this study provides valuable clinical insights into patient characteristics, complications to SS, resource use, and factors related to revision surgery in patients with CRSwNP.

Indexed as

Cost of IllnessHealth Care CostsNasal PolypsPostoperative ComplicationsRhinitisSinusitisAdultAgedChronic DiseaseCohort StudiesFemaleHumansIncidenceMaleMiddle AgedPrevalenceasthmachronic rhinosinusitisnasal polypssinus surgery

Identifiers

PMID40754756
PMCPMC12489017

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.