ArticleJournal of Alzheimer's disease : JAD2026
Characterizing olfaction, anxiety, and depression in subjective cognitive decline.
Article in Journal of Alzheimer's disease : JAD, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Olfactory decline in aging: longitudinal trajectories and associations with cognitive decline and postmortem neuropathology.medRxiv : the preprint server for health sciences · 2026Article
- Introduction to Supplement Issue: Sensory loss in Alzheimer's disease and related dementias.Journal of Alzheimer's disease : JAD · 2026Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BackgroundOlfactory dysfunction and neuropsychiatric symptoms are well-established hallmarks of Alzheimer's disease (AD) and serve as predictors of progression from mild cognitive impairment to AD. However, the literature remains unclear on whether olfactory dysfunction is already evident in the prodromal form of subjective cognitive decline (SCD).ObjectiveThis study aimed to characterize olfactory function and neuropsychiatric symptoms, including anxiety and depression, in individuals with SCD compared to healthy controls (HC).MethodsA total of 110 community-dwelling participants aged 60 years and older were recruited, with 59 classified as SCD (42 women) and 51 as HC (35 women). Participants completed validated anxiety and depression questionnaires (Geriatric Anxiety Inventory and Geriatric Depression Scale) and underwent a comprehensive olfactory assessment using the complete Sniffin' Sticks battery (odor threshold, discrimination, and identification).ResultsThe SCD group exhibited lower global olfactory scores (small to moderate effect size; Cohen's
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