ArticlePsychiatry investigation2025
Interactions Between Depression, Autonomic Dysfunction, Inhibitory Control and Reaction Time: Insights From Heart Rate Variability During Continuous Performance Test.
Article in Psychiatry investigation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
objectiveThis study investigates the relationship between depression, autonomic dysfunction, inhibitory control (IC), and reaction time by analyzing heart rate variability (HRV) during a cognitive task.
methodsA total of 29 healthy males and 25 males diagnosed with depression (aged 20-35 years) participated. HRV data were recorded during the Conners Continuous Performance Test-II (CCPT-II) in each group. HRV parameters, including mean RR intervals, standard deviation of normal-to-normal heartbeats (SDNN), low-frequency power with logarithm (lnLF), and high-frequency power with logarithm (lnHF), were analyzed and correlated with IC (d') and reaction time.
resultsThe depression group exhibited significantly lower lnHF values compared to the healthy group. SDNN and lnLF decreased in both groups during CCPT-II. In the healthy group, d' correlated significantly with SDNN, lnLF, and lnHF at t14 and across the test duration. However, in the depression group, only RR intervals correlated with d'. A significant correlation between reaction time and HRV was noted at t14 in the healthy group, suggesting autonomic nervous system (ANS) involvement in cognitive performance.
conclusionReaction time in healthy individuals correlated with ANS function during later stages of CCPT-II, whereas depression disrupted this association. The lower d' in the depression group was not due to a speed-accuracy trade-off but rather a more pronounced neural network impairment. These findings suggest that depression impairs both IC and autonomic regulation.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.