Evidence map›Paper›PMID 40756319›Full record

ReviewCurrent treatment options in cardiovascular medicine2025

Identifying Responders to Transcatheter Interventions for Secondary Mitral Regurgitation.

Diane Rizkallah, Carl Ammoury, Elio Haroun, Joseph El Roumi, Ben Alencherry, Rhonda Miyasaka, Amar Krishnaswamy, Samir Kapadia, Serge Harb, Deborah Kwon

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Current treatment options in cardiovascular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Diane Rizkallah *Heart, Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, OH USA.
Carl Ammoury *Heart, Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, OH USA.
Elio HarounHeart, Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, OH USA.
Joseph El RoumiHeart, Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, OH USA.
Ben AlencherryHeart, Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, OH USA.
Rhonda MiyasakaHeart, Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, OH USA.
Amar KrishnaswamyHeart, Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, OH USA.
Samir KapadiaHeart, Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, OH USA.
Serge HarbHeart, Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, OH USA.
Deborah KwonHeart, Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, OH USA.

Funding

Improving Phenotypic Classification and Prediction of Treatment Outcomes in Patients with Non-ischemic Cardiomyopathy and Functional Mitral RegurgitationR01HL170090 · NHLBI · CLEVELAND CLINIC LERNER COM-CWRU · PI DEBORAH KWON · 2023 to 2026
$3.1M
NHLBI NIH HHS R01 HL170090
6 · The paper itself

Abstract

Purpose of Review: This article offers a comprehensive review of the literature on imaging predictors of response to transcatheter interventions for secondary mitral regurgitation (SMR). Recent Findings: Recent advancements in percutaneous valve therapies have broadened treatment options for high-risk patients with SMR. While recent studies have demonstrated significant reduction in all-cause mortality and hospitalizations with transcatheter edge-to-edge repair (TEER), significant controversy remains. This review highlights the central role of multi-modality imaging to guide therapeutic decision making for optimal treatment response and long-term outcomes. Summary: Several echocardiographic, computerized tomography (CT) and cardiac magnetic resonance (CMR) imaging parameters are central to identifying optimal conditions for transcatheter therapies. Imaging features have become key predictors of outcomes following transcatheter interventions for secondary mitral regurgitation and provide important risk stratification to guide therapeutic decision making and shared decision making.

Indexed as

Cardiac magnetic resonanceComputerized tomographyEchocardiographyRisk stratificationSecondary mitral regurgitation

Identifiers

PMID40756319
PMCPMC12313785

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.