Evidence map›Paper›PMID 40756347›Full record

ArticleTheranostics2025

Unraveling α-synuclein and amylin co-aggregation: pathological insights and biomarker development for Parkinson's disease.

Yuhang Zhou, Minchao Lai, Bowen Shu, Benguo Wang, Dian Wang, Haoran Liu, Baowan Li, Jianhe Guo, Dongjie Hu, Mingyuan Li and 9 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Theranostics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Yuhang ZhouSchool of Medicine, The Chinese University of Hong Kong, Shenzhen, 518172, China.
Minchao LaiDepartment of Neurology, The First Affiliated Hospital of Shantou University Medical College, Shantou, Guangdong, 515041, China.
Bowen ShuDermatology Hospital, Southern Medical University, Guangzhou, Guangdong, 510091, China.
Benguo WangRehabilitation Department of the Second Affiliated Hospital, School of Medicine, The Chinese University of Hong Kong, Shenzhen & Longgang District People's Hospital of Shenzhen, Shenzhen, Guangdong, 518172, China.
Dian WangDepartment of Forensic Medicine, Shantou University Medical College (SUMC), Shantou, Guangdong, 515041, China.
Haoran LiuSchool of Science and Engineering, The Chinese University of Hong Kong, Shenzhen 518172, China.
Baowan LiSchool of Instrumentation Science and Engineering, Harbin Institute of Technology, Harbin, Heilongjiang, 150001, China.
Jianhe GuoGuangdong Provincial Key Laboratory of Sensing Technology and Biomedical Instrument, School of Biomedical Engineering, Sun Yat-Sen University, Shenzhen Campus of Sun Yat-Sen University, Shenzhen, 518107, China.
Dongjie HuSchool of Medicine, The Chinese University of Hong Kong, Shenzhen, 518172, China.
Mingyuan LiSchool of Medicine, The Chinese University of Hong Kong, Shenzhen, 518172, China.
Cheng ZhuGuangdong Provincial Key Laboratory of Materials and Technologies for Energy Conversion (MATEC), Guangdong Technion-Israel Institute of Technology, Shantou, 515063, China.
Muzhi KangDepartment of Materials Science and Engineering, Guangdong Technion-Israel Institute of Technology, Shantou, 515063, China.
Zhong Alan LiSchool of Biomedical Sciences, The Chinese University of Hong Kong, Shatin, NT, 999077, Hong Kong SAR, China.
Renzhi WangSchool of Medicine, The Chinese University of Hong Kong, Shenzhen, 518172, China.
Yongjuan ZhaoSchool of Medicine, The Chinese University of Hong Kong, Shenzhen, 518172, China.
Rocky S TuanSchool of Biomedical Sciences, The Chinese University of Hong Kong, Shatin, NT, 999077, Hong Kong SAR, China.
Keying GuoGuangdong Provincial Key Laboratory of Materials and Technologies for Energy Conversion (MATEC), Guangdong Technion-Israel Institute of Technology, Shantou, 515063, China.
Chenzhong LiSchool of Medicine, The Chinese University of Hong Kong, Shenzhen, 518172, China.
Cheng JiangSchool of Medicine, The Chinese University of Hong Kong, Shenzhen, 518172, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

alpha-SynucleinIslet Amyloid PolypeptideParkinson DiseaseAgedBiomarkersBrainExtracellular VesiclesFemaleHumansMaleMiddle AgedMultiple System AtrophyProtein Aggregatesalpha-SynucleinBiomarkersIslet Amyloid PolypeptideProtein AggregatesSNCA protein, human

Identifiers

PMID40756347
PMCPMC12315819

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.