ReviewInternational journal of biomaterials2025
Topical Delivery Systems for Plant-Derived Antimicrobial Agents: A Review of Current Advances.
Review in International journal of biomaterials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed.
- Nanotechnologies for Skin Drug Delivery: Polymeric, Bio-Based, and Hybrid Nanocarriers with Clinical and Translational Perspectives.Pharmaceuticals (Basel, Switzerland) · 2026Review
- Skin on Drugs: Psychotropic Compounds in Cutaneous Biology.International journal of molecular sciences · 2026Review
- Plant-Derived Peptide-Polymer Therapeutics for Cutaneous Infections and Inflammation: Mechanistic Basis, Delivery Design and Translational Considerations.Pharmaceutics · 2026Review
- Development and Characterization of aPharmaceutics · 2026Article
- Development of Nigella sativa essential oil loaded keratin/gelatin cryogel with antimicrobial and antioxidant properties for wound dressing.Scientific reports · 2026Article
- The Influence of Polyethyleneimine's Molecular Weight on the Physical, Chemical, and Biological Properties of Chitosan-Polyethyleneimine Carbon Dots and In Vitro Performances.Micromachines · 2026Article
- Hyaluronic-Acid Nanocapsules with Plant Extracts: Characterization and Antimicrobial Activity Against Skin Microbiota.Materials (Basel, Switzerland) · 2026Article
- Physicochemical and Functional Characterization ofFoods (Basel, Switzerland) · 2026Article
- Attenuation of biofilm-encoding genes and virulence attributes in clinical isolates of Acinetobacter baumannii by essential oil derived from Myroxylon balsamum.Scientific reports · 2026Article
- Antimicrobial and Antioxidant Effects of Aqueous, Methanolic, and a Deep Eutectic Solvent-Based Extracts ofScientifica · 2026Article
- Breaking biofilm barriers in skin wounds: Membrane-Active antimicrobials in an era of resistance.Current research in pharmacology and drug discovery · 2026Review
- Integrated Phenotypic and Transcriptomic Analyses Unveil the Antibacterial Mechanism of Punicalagin Against Methicillin-ResistantFoods (Basel, Switzerland) · 2025Article
- TiOMolecules (Basel, Switzerland) · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Plant-derived compounds have attracted considerable attention in the field of antimicrobial therapy. This interest is primarily due to their natural origin and historical evidence of their use in traditional medicine systems. These derivatives are a rich reservoir of chemical diversity that has a promising potential for the development and production of new antimicrobial agents with the least amount of side effects and risks of drug resistance. However, the delivery of plant-derived antimicrobial agents, especially through the topical route, poses significant challenges. As the largest organ of the body, the skin acts as a first barrier against the entrance of microbial pathogens. A primary limitation to transdermal delivery of plant-derived antimicrobial agents is their complex molecular structures, which often prevent effective absorption through the skin. Therefore, developing and promoting an effective local drug delivery system to increase the potential of antimicrobial therapy is very important and effective in public health. This review discusses delivery strategies for plant-derived antimicrobial agents aimed at the bioavailability and stability of these compounds as well as their mode of action, ensuring targeted delivery to the site of infection with long-lasting effects and minimizing side effects. Besides, various topical drug delivery platforms are analyzed, including nanoparticles, liposomes, and innovative application methods such as microneedles.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.