Evidence map›Paper›PMID 40756669›Full record

ReviewNeuro-oncology advances

Advancing vaccine-based immunotherapy in glioblastoma treatment.

Desh Deepak Singh, Shafiul Haque, Abhishek Kumar Singh, Dharmendra Kumar Yadav

Abstract readReview
In one paragraph

Review in Neuro-oncology advances. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Desh Deepak SinghAmity Institute of Biotechnology, Amity University Rajasthan, Jaipur, India.
Shafiul HaqueDepartment of Nursing, College of Nursing and Health Sciences, Jazan University, Jazan, Saudi Arabia and School of Medicine, Universidad Espiritu Santo, Samborondon, Ecuador.
Abhishek Kumar SinghManipal Centre for Biotherapeutics Research (MCBR), Manipal Centre for Biotherapeutics Research, Manipal Academy of Higher Education, Manipal, India.ORCID https://orcid.org/0000-0002-3186-9898
Dharmendra Kumar YadavDepartment of Biologics, College of Pharmacy, Gachon University, Yeonsu-gu, Incheon, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glioblastomas (GBMs) originate from glial cells and are characterized by aggressive growth and poor prognosis. Despite advances in surgical resection, complete elimination remains challenging, often leading to recurrence that is resistant to standard therapies. Immunotherapy and conventional treatments show promise in enhancing therapeutic outcomes across various cancers. Researchers continue to explore new treatments, particularly radiation, chemotherapy, and surgery; however, glioblastoma remains highly challenging, with only modest improvements in survival. Recent progress in immunotherapy, especially with tumor vaccines such as peptide-based and cell-based options (eg, dendritic cell vaccines), represents significant advancements despite the limitations observed in current clinical trials. This article reviews recent developments in vaccine-based immunotherapy for glioblastoma treatment.

Indexed as

glioblastomatumor antigenvaccine efficacyvaccine perspectivevaccine platform

Identifiers

PMID40756669
PMCPMC12314604

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.