ArticlePulmonary circulation2025
Characterization of the Population With Intermediate-Risk Status in Pulmonary Arterial Hypertension: Patients in a Latin American Country: The CAPRI Registry.
Article in Pulmonary circulation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pulmonary arterial hypertension (PAH) in intermediate-risk patients poses a challenge for clinicians, particularly in determining the optimal timing for escalating pharmacological treatment. We conducted a multicenter cross-sectional study that analyzed data from the Colombian Pulmonary Hypertension Network (HAPredCO) on patients diagnosed with PAH. Participants were stratified into low- and high-intermediate risk groups using the four-level ESC/ERS score, which incorporates optimized cutoff values for WHO functional class (WHO FC), the 6-min walk test (6MWT), and N-terminal pro-brain natriuretic peptide (NT-proBNP)/brain natriuretic peptide (BNP) concentration. A bivariate analysis was conducted to compare study variables at baseline and during clinical follow-up. Additionally, a survival analysis was performed using Kaplan-Meier curves to compare outcomes between the intermediate-risk groups. A total of 175 patients were analyzed, with a mean age of 44.85 years (SD 15.5), of which 86% (150/175) were women. In the baseline, a total of 75% (131/175) were classified as intermediate-low-risk. In clinical follow-up, 40% (61/154) were classified as intermediate-low-risk, 21% (32/154) were classified as intermediate-low-risk, 23% (35/154) were classified as intermediate-low-risk, and 16% (26/154) as intermediate-high-risk. At baseline, WHO FC III was 61% (107/174), compared to 35% (56/154) at follow-up (
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