Evidence mapPaperPMID 40758632Full record

ArticleAmerican journal of respiratory and critical care medicine2025

A Large-Scale Single-Cell Atlas Reveals the Peripheral Immune Panorama of Bacterial Pneumonia.

Kun Xiao, Yan Cao, Peng Yan, Ye Hu, Laurence Don Wai Luu, Pan Pan, Hongjun Gu, Zhimei Duan, Jiaxing Wang, Wei Chen and 9 more

Abstract read
In one paragraph

Article in American journal of respiratory and critical care medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Synergistic eradication of NDM-1Materials today. Bio · 2026
    Article
  2. Article
  3. Myeloid cell reprogramming drives enhanced defense againstbioRxiv : the preprint server for biology · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Trained immunity in respiratory diseases: Mechanisms of action and intervention strategies.Chinese medical journal pulmonary and critical care medicine · 2026
    Review
  8. Review
  9. Article
  10. Article
  11. Review
  12. Think Locally, Act Globally: Resolving the Peripheral Immune Milieu in Bacterial Pneumonia.American journal of respiratory and critical care medicine · 2025
    Article
  13. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

19 authors.

Kun XiaoCollege of Pulmonary & Critical Care Medicine, Chinese People's Liberation Army General Hospital, Beijing, People's Republic of China.ORCID 0000-0002-8039-3283
Yan CaoCollege of Pulmonary & Critical Care Medicine, Chinese People's Liberation Army General Hospital, Beijing, People's Republic of China.ORCID 0000-0002-1400-4243
Peng YanDepartment of Pulmonary and Critical Care Medicine, China Aerospace Science & Industry Corporation 731 Hospital, Beijing, People's Republic of China.
Ye HuCollege of Pulmonary & Critical Care Medicine, Chinese People's Liberation Army General Hospital, Beijing, People's Republic of China.
Laurence Don Wai LuuSchool of Life Sciences, University of Technology Sydney, Sydney, Australia.
Pan PanCollege of Pulmonary & Critical Care Medicine, Chinese People's Liberation Army General Hospital, Beijing, People's Republic of China.
Hongjun GuCollege of Pulmonary & Critical Care Medicine, Chinese People's Liberation Army General Hospital, Beijing, People's Republic of China.
Zhimei DuanCollege of Pulmonary & Critical Care Medicine, Chinese People's Liberation Army General Hospital, Beijing, People's Republic of China.
Jiaxing WangDepartment of Critical Care Medicine, The Eighth Medical Center of Chinese People's Liberation Army General Hospital, Beijing, People's Republic of China.
Wei ChenCollege of Pulmonary & Critical Care Medicine, Chinese People's Liberation Army General Hospital, Beijing, People's Republic of China.
Xuxin ChenCollege of Pulmonary & Critical Care Medicine, Chinese People's Liberation Army General Hospital, Beijing, People's Republic of China.
Jianhong ZhangRespiratory and Critical Care Medicine Department, Beijing Jingmei Group, General Hospital, Beijing, People's Republic of China.
Wailong ZouDepartment of Pulmonary and Critical Care Medicine, Aerospace Center Hospital, Beijing, People's Republic of China.
Peipei SunDepartment of Pulmonary and Critical Care Medicine, Peking University Shougang Hospital, Beijing, People's Republic of China; and.
Liang ChenRespiratory and Critical Care Medicine Department, Beijing Jingmei Group, General Hospital, Beijing, People's Republic of China.
Jichao ChenDepartment of Pulmonary and Critical Care Medicine, Aerospace Center Hospital, Beijing, People's Republic of China.
Pingchao XiangDepartment of Pulmonary and Critical Care Medicine, Peking University Shougang Hospital, Beijing, People's Republic of China; and.
Lixin XieCollege of Pulmonary & Critical Care Medicine, Chinese People's Liberation Army General Hospital, Beijing, People's Republic of China.
Yi WangExperimental Research Center, Capital Center for Children's Health, Capital Medical University, Capital Institute of Pediatrics, and.ORCID 0000-0002-2031-087X

Funding

National Key Research and Development Program of China 2021YFC2301101National Key Research and Development Program of China 2021YFC2301102National Science Foundation for Young Scientists of China 82100096
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Pneumonia, BacterialAdultAgedCase-Control StudiesFemaleHumansMaleMiddle AgedMonocytesSingle-Cell AnalysisTranscriptomebacterial pneumoniacytokine stormperipheral immune responsesingle-cell RNA sequencingT cell exhaustion

Identifiers

PMID40758632
PMCPMC12700268

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.