Scanning Electrochemical Impedance Microscopy-Based Assessment of Glucose Biosensors.

Antanas Zinovicius, Timas Merkelis, Juste Rozene, Sigita Bendinskaite, Inga Morkvenaite, Sheng-Tung Huang, Arunas Ramanavicius

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Article in Langmuir : the ACS journal of surfaces and colloids, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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Authors and funding

7 authors.

Antanas ZinoviciusDepartment of Mechatronics, Robotics, and Digital Manufacturing, Vilnius Gediminas Technical University, Plytinės g. 25, 10105 Vilnius, Lithuania.

Timas MerkelisDepartment of Physical Chemistry, Vilnius University, Naugarduko 24, 03225 Vilnius, Lithuania.

Juste RozeneDepartment of Mechatronics, Robotics, and Digital Manufacturing, Vilnius Gediminas Technical University, Plytinės g. 25, 10105 Vilnius, Lithuania.

Sigita BendinskaiteDepartment of Physical Chemistry, Vilnius University, Naugarduko 24, 03225 Vilnius, Lithuania.

Inga MorkvenaiteDepartment of Nanotechnology, Center for Physical Sciences and Technology, Saulėtekio 3, 10257 Vilnius, Lithuania.

Sheng-Tung HuangDepartment of Chemical Engineering and Biotechnology and Institute of Biochemical and Biomedical Engineering, National Taipei University of Technology, 106 Taipei, Taiwan.ORCID 0000-0003-0214-6436

Arunas RamanaviciusDepartment of Nanotechnology, Center for Physical Sciences and Technology, Saulėtekio 3, 10257 Vilnius, Lithuania.ORCID 0000-0002-0885-3556

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Scanning electrochemical impedance microscopy (SEIM) was assessed as an electrochemical method for developing glucose biosensors based on glucose oxidase (GOx). To determine the lowest detectable GOx activity, scanning electrochemical microscopy (SECM) in the feedback mode (FB-SECM) was applied. During the measurement procedure, an ultramicroelectrode (UME) was moved vertically over the surface modified by immobilized GOx. A positive feedback response of the FB-SECM mode was determined during the assessment of surfaces modified by 5 fg/mm

Indexed as

Biosensing TechniquesGlucoseGlucose OxidaseMicroscopy, Electrochemical, ScanningElectric ImpedanceElectrodesEnzymes, ImmobilizedKineticsSurface PropertiesEnzymes, ImmobilizedGlucoseGlucose Oxidase

Identifiers

PMID40758861

DOI10.1021/acs.langmuir.5c02292

PMCPMC12632180

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