Evidence map›Paper›PMID 40759861›Full record

ReviewArchives of pharmacal research2025

Insights into biological activities profile of gingerols and shogaols for potential pharmacological applications.

Anis Najwa Abdul Rani, Anand Gaurav, Vannajan Sanghiran Lee, Nadiah Mad Nasir, Sharifuddin Md Zain, Vaishali M Patil, Ming Tatt Lee

Abstract readReview
PubMed Publisher
In one paragraph

Review in Archives of pharmacal research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Anis Najwa Abdul RaniFaculty of Pharmaceutical Sciences, UCSI University, 56000, Kuala Lumpur, Malaysia.
Anand GauravDepartment of Pharmaceutical Sciences, School of Health Sciences and Technology, UPES, Dehradun, Uttarakhand, 248007, India. anand.pharma@gmail.com.ORCID http://orcid.org/0000-0003-1039-064X
Vannajan Sanghiran LeeFaculty of Science, Universiti Malaya, 50603, Kuala Lumpur, Malaysia.
Nadiah Mad NasirDepartment of Chemistry, Faculty of Science, Universiti Putra Malaysia, 43400, Selangor, Malaysia.
Sharifuddin Md ZainFaculty of Science, Universiti Malaya, 50603, Kuala Lumpur, Malaysia.
Vaishali M PatilCharak School of Pharmacy, Chaudhary Charan Singh University (CCSU), Meerut, Uttar Pradesh, 250004, India.
Ming Tatt LeeFaculty of Pharmaceutical Sciences, UCSI University, 56000, Kuala Lumpur, Malaysia. leemt@ucsiuniversity.edu.my.ORCID http://orcid.org/0000-0003-3957-2439

Funding

Kementerian Pendidikan Malaysia FRGS/1/2021/SKK06/UCSI/02/4Kementerian Pendidikan Malaysia FRGS/1/2021/WAB13/UCSI/02/1
6 · The paper itself

Abstract

Ginger (Zingiber officinale) rhizome has been widely used in traditional medicine for centuries to promote good health and well-being, treating conditions such as diarrhea, stomach discomfort, nausea, cholera, asthma, and respiratory diseases. Gingerol and shogaol are essential bioactive phenolic compounds abundantly found in fresh and dried ginger and have been extensively studied using modern technology to evaluate their therapeutic effects. These phenolic compounds demonstrate a wide range of properties, including antioxidant, anti-inflammatory, antidiabetic, and anticancer effects, which operate through various mechanisms. Furthermore, researchers have utilized the chemical structures of gingerol and shogaol as templates to develop novel, safer, and more effective drugs for treating multiple illnesses. This review article focuses on previous literature assessing the potential efficacy of these compounds as therapies based on their antioxidant, anti-inflammatory, antidiabetic, anticancer, and neuroprotective properties.

Indexed as

Antineoplastic Agents, PhytogenicAntioxidantsCatecholsFatty AlcoholsZingiber officinaleAnimalsAnti-Inflammatory AgentsHumansHypoglycemic AgentsNeuroprotective AgentsAnti-Inflammatory AgentsAntineoplastic Agents, PhytogenicAntioxidantsCatecholsFatty AlcoholsgingerolHypoglycemic AgentsNeuroprotective AgentsshogaolAntidiabeticAnti-inflammatoryAntioxidantsGingerolPhenolic compoundsShogaol

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.