Evidence mapPaperPMID 40760409Full record

ArticleBMC infectious diseases2025

Determining population-specific risk factors for COVID-19 susceptibility and severity to inform future individual-level integrated risk scoring.

Ilham Morani, Haneen Shibli, David Karasik, Michael Edelstein

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In one paragraph

Article in BMC infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ilham MoraniThe Azrieli Faculty of Medicine, Bar-Ilan University, Safed, 1311502, Israel. ilhammorani@gmail.com.
Haneen ShibliThe Azrieli Faculty of Medicine, Bar-Ilan University, Safed, 1311502, Israel.
David KarasikThe Azrieli Faculty of Medicine, Bar-Ilan University, Safed, 1311502, Israel.
Michael EdelsteinThe Azrieli Faculty of Medicine, Bar-Ilan University, Safed, 1311502, Israel.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesAcute respiratory tract infections (ARI), including COVID-19, are a significant global health challenge with pandemic potential. Understanding factors influencing ARI susceptibility and severity in different populations is crucial for pandemic preparedness and mitigation. We investigated epidemiological risk factors for COVID-19 susceptibility and severity in the Israeli population.

methodsParticipants who took a COVID-19 PCR test between July 2021 and August 2022 completed an online survey including demographics, comorbidities, infection and vaccination status. We identified factors associated with SARS-CoV-2 infection and disease severity using logistic regression and compared our results with the global literature.

resultsWe included 2128 participants. Of these 823 participants were tested positive for SARS-CoV-2. Individuals without COPD and BMI > 30 had higher infection odds (aOR = 6.21, 95% CI:1.42-27.25 and aOR = 1.54, 95% CI:1.02-2.32; respectively). High school-level education was associated with increased susceptibility and severity compared to higher education (aOR = 1.55, 95% CI:1.1-2.18 and aOR = 2.80, 95% CI 1.62-4.86; respectively). Hospitalization was associated with older age (p < 0.001). Vaccination with 3 doses significantly reduced infection and hospitalization risk compared to unvaccinated (aOR = 0.024, 95% CI:0.016-0.04 and aOR = 0.37, 95% CI: 0.17-0.81; respectively, p < 0.05). Compared to Arab participants, Jewish ones were less likely to be infected (aOR = 1.48, 95% CI:1.02-2.15, p < 0.05).

conclusionsIdentified risk factors are consistent with meta-analyses of studies from other countries. Similar to other countries, minority groups were found to be at higher risk, therefore risk models predicting ARI susceptibility and severity have to take this into account.

Indexed as

COVID-19AdolescentAdultAgedDisease SusceptibilityFemaleHumansIsraelMaleMiddle AgedRisk FactorsSARS-CoV-2Severity of Illness IndexYoung AdultAcute respiratory tract infectionCoronavirus (COVID-19)Epidemiological risk factorsIsrael

Identifiers

PMID40760409
PMCPMC12323152

What Socratic holds

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.