ArticleEuropean journal of medical research2025
Difference between estimated glomerular filtration rate based on cystatin c versus creatinine and risk of hypertension: a prospective cohort study.
Article in European journal of medical research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Serum cystatin C as a biomarker for diabetic retinopathy and its role in diabetic retinopathy-diabetic kidney disease comorbidity.Journal of translational medicine · 2026Article
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Abstract
objectivesThe impact of the difference between cystatin C- and creatinine-based estimated glomerular filtration rate (eGFRdiff) on hypertension remains unknown. We investigated the association of eGFRdiff and the risk of developing hypertension.
methodsA total of 3628 participants without hypertension at baseline in 2011 from the China Health and Retirement Longitudinal Study were enrolled. The eGFRdiff was calculated using both absolute difference (eGFRabdiff = eGFRcys-eGFRcr) and the ratio (eGFRrediff = eGFRcys/eGFRcr) between cystatin C- and creatinine-based estimated glomerular filtration rate. The association between eGFRdiff and hypertension risk was examined using restricted cubic spline (RCS) and multivariable logistic regression analysis.
resultsThe mean (± SD) for eGFRabdiff and eGFRrediff were - 16.3 ± 16.5 mL/min/1.73 m
conclusionsA large negative difference in cystatin C-based and creatinine-based eGFR was significantly associated with the risk of hypertension. Our findings suggested that monitoring eGFRdiff could be clinically useful in identifying high-risk people for hypertension.
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