Evidence map›Paper›PMID 40761228›Full record

ArticleFrontiers in cardiovascular medicine2025

Correlation between α-ketoglutarate and the oxidative stress response in patients with coronary heart disease and prognostic analysis of interventional therapy for coronary heart disease.

Huantang Deng, Yu Zhang

Abstract read
In one paragraph

Article in Frontiers in cardiovascular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Huantang DengDepartment of Cardiology, Huizhou Municipal Central Hospital, Huizhou, Guangdong, China.
Yu ZhangDepartment of Cardiology, Huizhou Municipal Central Hospital, Huizhou, Guangdong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To explore the correlation between α-ketoglutarate and the oxidative stress response in patients with coronary heart disease (CHD) and to analyze the prognosis of CHD patients receiving interventional treatment. Methods: A total of 318 CHD patients admitted from September 2020 to September 2023 were selected and divided into a conservative medical treatment group (159 patients) and an interventional treatment group (159 patients) according to the treatment plan. The interventional treatment group was divided into an event group and a nonevent group according to whether the primary endpoint event occurred; another 59 patients with healthy physical examination results during the same period composed the control group. The results: The serum TAC, SOD, CAT, and GSH levels in the conservative medical treatment group were lower than those in the control group ( Conclusion: α-Ketoglutarate is related to oxidative stress in patients with CHD. The lower the serum α-ketoglutarate level is, the greater the likelihood that adverse events will occur.

Indexed as

coronary heart diseaseinterventional therapyoxidative stressprognosis assessmentα-ketoglutarate

Identifiers

PMID40761228
PMCPMC12318753

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.