Evidence map›Paper›PMID 40761402›Full record

ReviewFrontiers in pharmacology2025

Pharmacogenetics or predictive genetics? APOE testing blurs the lines.

Stefania Zampatti, Cristina Peconi, Juliette Farro, Fabrizio Piras, Clelia Pellicano, Carlo Caltagirone, Emiliano Giardina

Abstract readReview
In one paragraph

Review in Frontiers in pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Stefania ZampattiGenomic Medicine Laboratory UILDM, IRCCS Santa Lucia Foundation, Rome, Italy.
Cristina PeconiGenomic Medicine Laboratory UILDM, IRCCS Santa Lucia Foundation, Rome, Italy.
Juliette FarroGenomic Medicine Laboratory UILDM, IRCCS Santa Lucia Foundation, Rome, Italy.
Fabrizio PirasNeuropsychiatry Laboratory, Department of Clinical Neuroscience and Neurorehabilitation, IRCCS Santa Lucia Foundation, Rome, Italy.
Clelia PellicanoNeuropsychiatry Laboratory, Department of Clinical Neuroscience and Neurorehabilitation, IRCCS Santa Lucia Foundation, Rome, Italy.
Carlo CaltagironeDepartment of Clinical and Behavioral Neurology, IRCCS Fondazione Santa Lucia, Rome, Italy.
Emiliano GiardinaGenomic Medicine Laboratory UILDM, IRCCS Santa Lucia Foundation, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The integration of pharmacogenetics into personalized medicine enables the optimization of drug selection and dosage, maximizing therapeutic benefits while minimizing the risk of adverse drug reactions. The association between

Indexed as

alzheimer diseaseAPOEARIAgenetic counsellingmonoclonal antibodiespharmacogeneticspredictive test

Identifiers

PMID40761402
PMCPMC12318987

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.