Evidence map›Paper›PMID 40761545›Full record

ReviewFrontiers in bioengineering and biotechnology2025

Nanomaterials engineered for photothermal therapy in neural tumors and neurodegenerative diseases: biomaterial design, clinical mechanisms and applications.

Hanjing Zhu, Wei Yang, Yijun Suo, Ye Liu, Xinyi Zhan, Jun Zhou, Zhiying Chen, Xiangbing Wu, Xiaoping Yin, Bing Bao

Abstract readReview
In one paragraph

Review in Frontiers in bioengineering and biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Dynamic Hydrogels in Breast Tumor Models.Gels (Basel, Switzerland) · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Hanjing Zhu *Department of Neurology, Affiliated Hospital of Jiujiang University, Jiujiang, China.
Wei Yang *Department of Neurology, Affiliated Hospital of Jiujiang University, Jiujiang, China.
Yijun SuoDepartment of Neurology, Affiliated Hospital of Jiujiang University, Jiujiang, China.
Ye LiuDepartment of Neurology, Affiliated Hospital of Jiujiang University, Jiujiang, China.
Xinyi ZhanDepartment of Neurology, Affiliated Hospital of Jiujiang University, Jiujiang, China.
Jun ZhouDepartment of Neurology, Affiliated Hospital of Jiujiang University, Jiujiang, China.
Zhiying ChenDepartment of Neurology, Affiliated Hospital of Jiujiang University, Jiujiang, China.
Xiangbing WuDepartment of Neurology, Affiliated Hospital of Jiujiang University, Jiujiang, China.
Xiaoping YinDepartment of Neurology, Affiliated Hospital of Jiujiang University, Jiujiang, China.
Bing BaoDepartment of Neurology, Affiliated Hospital of Jiujiang University, Jiujiang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The rising incidence of neural tumors and neurodegenerative diseases cause significant health, emotional, and financial burdens. Conventional treatments like surgery and chemotherapy often lack effectiveness. However, advancements in nanotechnology, particularly photothermal therapy (PTT), offer new hope. PTT is widely studied for neural tumors and neurodegenerative diseases due to its simplicity, rapid recovery, combined therapeutic potential, and compatibility with imaging techniques. This innovative approach could revolutionize the diagnosis and treatment of neural tumors and neurodegenerative diseases, addressing current limitations and improving outcomes. In this article, we offer a comprehensive overview of the rational design and engineering of various nanomaterials designed specifically for PTT applications in neural tumors and neurodegenerative diseases, including organic platforms such as liposomes, dopamine, etc. and inorganic platforms such as gold nanomaterials, carbon nanomaterials, etc. A comparative analysis of these platforms examines their biocompatibility and potential for biodegradation. It also assesses their manufacturing scalability, cost-effectiveness, regulatory challenges, and ultimate potential for clinical translation. We also update the therapeutic advances of PTT in neural tumors (Glioma, Peripheral nerve sheath tumors, Spinal metastases from

Indexed as

blood-brain barriercombination therapygliomaheat shock proteins (HSP)inorganic nanoplatformneurodegenerative diseasesorganic nanoplatformphotothermal therapy (PTT)

Identifiers

PMID40761545
PMCPMC12319051

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.