Evidence map›Paper›PMID 40762506›Full record

ArticleAsian journal of andrology2026

Urgent need for inclusion of male infertility in global health strategies: insights from the GBD 2021 Study.

Long Zhong, Jia-Xu Gu, Cui Li, Suo-Lei Sun, Ming-Jia Chen, Yong Li, Yu Ding, Liang-Chao Ni, Yu Yang

Abstract read
In one paragraph

Article in Asian journal of andrology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Long ZhongShenzhen University Medical School, Shenzhen University, Shenzhen 518055, China.
Jia-Xu GuPeking University Health Science Center, Peking University, Beijing 100191, China.
Cui LiNingbo University Health Science Center, Ningbo 315211, China.
Suo-Lei SunDepartment of Urology, Peking University Shenzhen Hospital, Shenzhen 518036, China.
Ming-Jia ChenShenzhen University Medical School, Shenzhen University, Shenzhen 518055, China.
Yong LiShenzhen University Medical School, Shenzhen University, Shenzhen 518055, China.
Yu DingDepartment of Urology, Peking University Shenzhen Hospital, Shenzhen 518036, China.
Liang-Chao NiDepartment of Urology, Peking University Shenzhen Hospital, Shenzhen 518036, China.
Yu YangDepartment of Urology, Peking University Shenzhen Hospital, Shenzhen 518036, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study examines the global burden and prevalence of male infertility using data from the Global Burden of Disease Study 2021 (GBD 2021 Study), encompassing 204 countries from 1990 to 2021. By analyzing disability-adjusted life years (DALYs) and prevalence trends, alongside lifestyle, environmental, and disease-related factors, including the impact of coronavirus disease 2019 (COVID-19), we identified significant temporal and regional disparities. Using joinpoint regression, decomposition analysis, and Bayesian age-period-cohort models, the results revealed a rising global burden, with DALYs increasing from 15.8 to 18.6 per 100 000 and the age-standardized prevalence rising from 2752.5 to 3218.9 per 100 000 over three decades. Low- and middle-sociodemographic index (SDI) regions presented the highest burden, driven by demographic shifts and epidemiological challenges. The COVID-19 pandemic further exacerbated healthcare disparities, particularly in resource-limited settings. These findings underscore the urgent need to integrate male infertility into global health agendas, emphasizing tailored interventions and policy reforms to address socioeconomic impacts and mitigate rising burdens, especially in low- and middle-SDI regions.

Indexed as

COVID-19Global HealthInfertility, MaleAdultDisability-Adjusted Life YearsGlobal Burden of DiseaseHealthcare DisparitiesHumansMaleMiddle AgedPrevalenceSARS-CoV-2disability-adjusted life yearsjoinpoint regressionmale infertilityprevalencepublic health

Identifiers

PMID40762506
PMCPMC12912751

What Socratic holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.