Evidence map›Paper›PMID 40762933›Full record

ReviewMolecular diversity2026

Green chemistry for prostate health: exploring nature's toolbox against cancer, inflammation, and hyperplasia.

Muavia Sarwar, Hafiz Muhammad Irfan, Alamgeer, Zeeshan Jabbar, Mulazim Hussain Asim, Muhammad Sajjad Hassan, Shoaib Nawaz

Abstract readReview
PubMed Publisher
In one paragraph

Review in Molecular diversity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Muavia SarwarDepartment of Pharmacology, Faculty of Pharmacy, University of Sargodha, Sargodha, 40100, Punjab, Pakistan. mauvia.sarwar@gmail.com.
Hafiz Muhammad IrfanDepartment of Pharmacology, Faculty of Pharmacy, University of Sargodha, Sargodha, 40100, Punjab, Pakistan. muhammad.irfan@uos.edu.pk.
AlamgeerPunjab University College of Pharmacy, University of the Punjab, Lahore, 54000, Punjab, Pakistan.
Zeeshan JabbarDepartment of Pharmacology, Faculty of Pharmacy, University of Sargodha, Sargodha, 40100, Punjab, Pakistan.
Mulazim Hussain AsimDepartment of Pharmaceutics, Faculty of Pharmacy, University of Sargodha, Sargodha, 40100, Punjab, Pakistan.
Muhammad Sajjad HassanDepartment of Pharmacology, Faculty of Pharmacy, University of Sargodha, Sargodha, 40100, Punjab, Pakistan.
Shoaib NawazDepartment of Pharmacy, The University of Lahore, Sargodha campus, Sargodha, 40100, Punjab, Pakistan.

Funding

Higher Education Commission, Pakistan 315-24420-2BS3-232
6 · The paper itself

Abstract

This study explores the potential of phytochemicals as an innovative and successful strategy for mitigating symptoms of benign prostatic hyperplasia and prostate cancer. Prostate cancer is the most prevalent and second highest cause of mortality for men, with over 121 million cases worldwide. Finding no comprehensive study on the impact of compounds from all phytochemical classes in the perspectives of prostate disorders, this study analyzed data from a variety of investigations, including preclinical studies, in vitro and in vivo experiments, clinical trials, and cell line investigations, as part of a review of the literature. With a focus on mechanisms such as aging and hormonal factor modulation, apoptosis induction, overcoming inflammation, metabolic crisis, and medication resistance while minimizing side effects, the search concentrated on the effects of natural substances on prostate hyperplastic and malignant cells. The sequel of the study is suggestive of strong anti-hyperplastic and anti-cancerous potentials of phytochemicals in prostate cells. These phytochemicals have the capacity to target several pathways, providing a multifaceted approach to the therapy of BPH and prostate cancer. Interestingly, a large number of these substances exhibit negligible side effects, suggesting their possible use in clinical settings. The study unveils the mechanistic role of compounds belonging to various phytochemical classes in improving life quality and longevity in men with BPH and prostate cancer. Besides associating the existing literature, outcomes of the study ignite encouraging prospects towards further advancements in drug discovery and anticipation for prompt therapies.

Indexed as

Green Chemistry TechnologyInflammationPhytochemicalsProstateProstatic HyperplasiaProstatic NeoplasmsAnimalsHumansMalePhytochemicalsApoptosisBenign prostatic hyperplasia (BPH)Cell lineInflammationPhytochemicalsProstate cancer

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.