Evidence mapPaperPMID 40763073Full record

ArticleEuropean journal of heart failure2025

Atrial cardiomyopathy: From healthy atria to atrial failure. A clinical consensus statement of the Heart Failure Association of the ESC.

Jerremy Weerts, Otilia Țica, Julia Aranyo, Christian Basile, Angelina Borizanova-Petkova, Josip Andjelo Borovac, Massimiliano Camilli, Martin Eichenlaub, Emiliano Fiori, Tim Van Loon and 17 more

Abstract readConsensus Statement
In one paragraph

Article in European journal of heart failure, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed.

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  16. Association of non-invasive atrial cardiomyopathy markers with cerebral stroke lesions: a population-based analysis from the Hamburg City Health Study.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2026
    Article
  17. Review
  18. Atrial Cardiomyopathy.Maedica · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

27 authors.

Jerremy Weerts *Department of Cardiology, Cardiovascular Research Institute Maastricht, Maastricht, University Medical Centre, Maastricht, The Netherlands.ORCID https://orcid.org/0000-0002-9369-3453
Otilia Țica *Department of Cardiovascular Sciences, University of Birmingham, Birmingham, UK.ORCID https://orcid.org/0000-0002-6019-122X
Julia AranyoHeart Institute, Germans Trias i Pujol University Hospital, Badalona, Spain.
Christian BasileDepartment of Advanced Biomedical Sciences, University of Naples 'Federico II', Naples, Italy.
Angelina Borizanova-PetkovaDepartment of Emergency Medicine, Medical University Sofia, Sofia, Bulgaria.
Josip Andjelo BorovacCardiovascular Diseases Department, University Hospital of Split (KBC Split), Split, Croatia.
Massimiliano CamilliDepartment of Cardiovascular Medicine, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Martin EichenlaubDepartment of Cardiology and Angiology, Medical Center, University of Freiburg, Bad Krozingen, Germany.
Emiliano FioriDepartment of Clinical and Molecular Medicine, Sapienza University of Rome, Rome, Italy.
Tim Van LoonDepartment of Biomedical Engineering, Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands.
Coenraad WithaarDepartment of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Diana ZakarkaitėClinic of Cardiac and Vascular Diseases, Faculty of Medicine, Vilnius University, Vilnius, Lithuania.
Matthias D ZinkOrtenau-Klinikum Lahr, Academic Teaching Hospital University of Freiburg, Lahr, Germany.
Marianna AdamoCardiology Unit, ASST Spedali Civili di Brescia, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, Brescia, Italy.
Alberto AimoCardiology Division, Fondazione Toscana Gabriele Monasterio, Health Sciences Interdisciplinary Center, Scuola Superiore Sant'Anna, Pisa, Italy.
Elena ArbeloArrhythmia Section, Cardiology Department, Hospital Clínic, Universitat de Barcelona, Barcelona, Spain.
Felipe Bisbal Van BylenHeart Institute, Germans Trias i Pujol University Hospital, Badalona, Spain.
Dimitrios T FarmakisHeart Failure Unit, Department of Cardiology, Athens University Hospital Attikon, National and Kapodistrian University of Athens Medical School, Athens, Greece.
Dobromir DobrevInstitute of Pharmacology, Faculty of Medicine, University Duisburg-Essen, Essen, Germany.
Jelena ČelutkienėCentre of Innovative Medicine, Vilnius, Lithuania.
Michael BöhmKardiologie, Angiologie und Internistische Intensivmedizin, Homburg, Germany.
Andrew CoatsCAG Cardiovascular, St George's University Hospital, London, UK.
Marco MetraCardiology Unit, ASST Spedali Civili di Brescia, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, Brescia, Italy.
Giuseppe RosanoDepartment of Human Sciences and Promotion of Quality of Life, San Raffaele University of Rome, Rome, Italy.
Frank RuschitzkaCenter for Translational and Experimental Cardiology, Department of Cardiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Antoni Bayes-Genis *Heart Institute, Germans Trias i Pujol University Hospital, Badalona, Spain.ORCID https://orcid.org/0000-0002-3044-197X
Dipak Kotecha *Department of Cardiovascular Sciences, University of Birmingham, Birmingham, UK.ORCID https://orcid.org/0000-0002-2570-9812

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The importance of atrial cardiomyopathy (AtCM) as a specific clinical entity is increasingly recognized. Past definitions have varied, and the lack of consistent cut-offs for imaging parameters and biomarkers have limited clinical utility to diagnose and track AtCM progression. While research has mainly focused on AtCM in the context of atrial fibrillation, emerging evidence underscores its relevance in remodelling and development of heart failure. The aim of this consensus document was to provide a contemporary framework for AtCM, evolve the definitions of AtCM and atrial failure for more widespread clinical use, and help to direct emerging research and future clinical trials. Supporting the work of early career researchers, this consensus document evaluates diagnostic markers and summarizes the underpinning mechanisms, clinical characteristics and prognostic impact of AtCM. Our objective was to bring together new translational scientific progress, catalyse future research and enable clinical application to facilitate better management, for example in patient groups where aggressive control of risk factors or comorbidities could prevent AtCM progression. We redefined AtCM as a graded disorder that includes electrical dysfunction of the atria along with evidence of either mechanical atrial dysfunction, atrial enlargement and/or atrial fibrosis. Atrial failure is the end-stage manifestation of AtCM, characterized by progressive structural, electrophysiological and functional changes. Earlier identification, risk stratification and ongoing research into therapeutic options have the potential to prevent the clinical consequences of AtCM and atrial failure, including adverse patient outcomes and poor quality of life associated with atrial fibrillation and heart failure.

Indexed as

Atrial FibrillationCardiomyopathiesHeart AtriaHeart FailureSocieties, MedicalAtrial RemodelingDisease ProgressionHumansPrognosisAtrial cardiomyopathyAtrial fibrillationAtrial fibrosisElectrocardiographyHeart failureImaging

Identifiers

PMID40763073
PMCPMC12765236

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.