ArticleEcotoxicology and environmental safety2025
Diesel exhaust induces gut microbiome dysbiosis and reduced fecal acetate: Role of acetate supplementation.
Abstract read
In one paragraph
Article in Ecotoxicology and environmental safety, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Air Pollution Triggers Metabolomic Signature of Mitochondrial Dysfunction in Mice and Humans: Implications for Cardiovascular Disease Development.Arteriosclerosis, thrombosis, and vascular biology · 2026Article
- Linking Gut Microbiota, Mitochondrial Redox Dysfunction, and Ferroptosis in Cardiometabolic Diseases: A Narrative Review of Mechanistic Evidence and Redox-Targeted Interventions.Antioxidants (Basel, Switzerland) · 2026Review
- Ultrafine particulate matter exposure induces gut microbiota dysbiosis together with ER stress in the liver and worsened atherosclerosis.Environment international · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Rajat GuptaDivision of Cardiology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA; Environmental and Molecular Toxicology Interdepartmental Program, University of California Los Angeles, Los Angeles, CA, USA; Department of Environmental Health Sciences, Fielding School of Public Health, University of California Los Angeles, Los Angeles, CA, USA.
Candace ChangDivision of Cardiology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA; Environmental and Molecular Toxicology Interdepartmental Program, University of California Los Angeles, Los Angeles, CA, USA; Department of Environmental Health Sciences, Fielding School of Public Health, University of California Los Angeles, Los Angeles, CA, USA; Vatche and Tamar Manoukian Division of Digestive Diseases, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.
Laurent VergnesDepartment of Human Genetics, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.
Dawoud SulaimanDivision of Cardiology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.
Fen YinDivision of Cardiology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.
James A StewartDepartment of Environmental and Occupational Health Sciences, University of Washington, Seattle, WA, USA.
Margarete MehrabianDivision of Cardiology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.
Joel D KaufmanDepartment of Environmental and Occupational Health Sciences, University of Washington, Seattle, WA, USA.
Jonathan P JacobsEnvironmental and Molecular Toxicology Interdepartmental Program, University of California Los Angeles, Los Angeles, CA, USA; Vatche and Tamar Manoukian Division of Digestive Diseases, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA; Division of Gastroenterology, Hepatology and Parenteral Nutrition, Veterans Administration Greater Los Angeles Healthcare System, Los Angeles, CA, USA; Goodman-Luskin Microbiome Center, University of California Los Angeles, Los Angeles, CA, USA.
Aldons J LusisDivision of Cardiology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA; Department of Human Genetics, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA; Department of Microbiology, Immunology and Molecular Genetics, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA; Molecular Biology Institute, University of California Los Angeles, Los Angeles, CA, USA.
Karen ReueDepartment of Human Genetics, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.
Michael E RosenfeldDepartment of Environmental and Occupational Health Sciences, University of Washington, Seattle, WA, USA; Department of Pathology, University of Washington, Seattle, WA, USA.
Jesus A AraujoDivision of Cardiology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA; Environmental and Molecular Toxicology Interdepartmental Program, University of California Los Angeles, Los Angeles, CA, USA; Department of Environmental Health Sciences, Fielding School of Public Health, University of California Los Angeles, Los Angeles, CA, USA; Molecular Biology Institute, University of California Los Angeles, Los Angeles, CA, USA. Electronic address: JAraujo@mednet.ucla.edu.
Funding
Systems genomics of metabolic syndrome traitsP01HL028481 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI LUSIS, ALDONS JAKE · 1985 to 2019
$50.2MXENOBIOTIC BIOTRANSFORMATION AND DISPOSITIONP30ES007033 · NIEHS · UNIVERSITY OF WASHINGTON · PI Sheela Sathyanarayana · 1995 to 2026
$42.5MProject 5: ROS, Glutathione and Vascular Response to Diesel ExhaustP50ES015915 · NIEHS · UNIVERSITY OF WASHINGTON · PI KAUFMAN, JOEL DANIEL · 2008 to 2012
$11.8MDissecting the Role of Arachidonic Acid Metabolic Pathways Involved in Resolution Versus Progression of PM-Induced Cardiometabolic ToxicityR01ES033703 · NIEHS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Jesus Antonio Araujo · 2022 to 2026
$3.3MEffects of particulate air pollution on HDL function and atherosclerosisR01ES016959 · NIEHS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ARAUJO, JESUS ANTONIO · 2009 to 2013
$2.4MSex Differences in Postprandial Lipid MetabolismR01DK128898 · NIDDK · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Karen Reue, Peixiang Zhang · 2022 to 2026
$2.2MRole of Intestinal Microbiota in Dyslipidemia and Atherosclerosis Induced by Ambient Ultrafine ParticlesR01ES029395 · NIEHS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ARAUJO, JESUS ANTONIO, HSIAI, TZUNG K · 2018 to 2022
$2.2MInterplay Between Macrophages, Lipid Oxidation and the Nrf2/HO-1 Axis in the Cardiometabolic Toxicity Induced by Ultrafine ParticlesR01ES032806 · NIEHS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ARAUJO, JESUS ANTONIO · 2021 to 2025
$2.0MEffects of particulate air pollution on HDL function and athersclerosisR56ES016959 · NIEHS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ARAUJO, JESUS ANTONIO · 2014 to 2014
$154kNHLBI NIH HHS P01 HL028481NIDDK NIH HHS R01 DK128898NIEHS NIH HHS P30 ES007033NIEHS NIH HHS P50 ES015915NIEHS NIH HHS R01 ES016959NIEHS NIH HHS R01 ES029395NIEHS NIH HHS R01 ES032806NIEHS NIH HHS R01 ES033703NIEHS NIH HHS R56 ES016959
Abstract
Air pollution exposure enhances the risk of cardiovascular morbidity and mortality. Epidemiological studies provide strong evidence of a link between exposure to ambient particulate matter with aerodynamic diameter< 2.5 µm (PM
Indexed as
AcetatesAir PollutantsDysbiosisGastrointestinal MicrobiomeParticulate MatterVehicle EmissionsAnimalsFecesHep G2 CellsHumansMaleMiceMice, Inbred C57BLAcetatesAir PollutantsParticulate MatterVehicle EmissionsDyslipidemiasGut microbiomeLipoxygenaseMitochondrial dysfunctionParticulate matterShort chain fatty acidsTriglycerides
Identifiers
What Socratic holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.