ArticleMikrochimica acta2025
DNAzyme-driven dual-cycle coupled with pregnancy test strip signal transduction for monitoring of Dreissena polymorpha.
Article in Mikrochimica acta, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Authors and funding
4 authors.
Funding
Abstract
Dreissena polymorpha, an invasive species in North America, poses a serious threat to the environment and economy. It suffocates native species and clogs infrastructure, disrupting ecosystems. Since this species can also indicate biological pollution in water bodies, early monitoring can enable effective intervention and control measures to mitigate ecological and economic losses. Herein, a strategy was constructed for Dreissena polymorpha DNA detection with enzyme-assisted target recovery coupling DNAzyme-driven double-cycle signal amplification. This detection method utilizes the signal transduction mode of commercial pregnancy test strips. Magnetic beads conjugated with H1 (MB-H1) are hybridized to human chorionic gonadotropin-coupled H2 (hCG-H2). Target binding triggers toehold-mediated strand displacement. The cleavage of the endonuclease releases the target and hCG-H2 and generates DNAzyme. The DNAzyme, activated by Mn
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Registered trials
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