Evidence map›Paper›PMID 40764522›Full record

ArticleBMC geriatrics2025

Predictive role of the geriatric nutritional risk index in all-cause and cardiovascular mortality among elderly patients with osteoarthritis.

Zong Jiang, Xin Cai, Weiya Lan, Zexu Jin, Jiajun Liu, Fang Tang, Haixia Fan

Erratum issuedAbstract read
In one paragraph

Article in BMC geriatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Zong Jiang *Second Clinical Medical College, Guizhou University of Traditional Chinese Medicine, Guiyang, 550001, China.
Xin Cai *Department of Rheumatology and Immunology, The First People's Hospital Of Guiyang, Guiyang, 550001, China.
Weiya LanSecond Clinical Medical College, Guizhou University of Traditional Chinese Medicine, Guiyang, 550001, China.
Zexu JinDepartment of Rheumatology and Immunology, The First People's Hospital Of Guiyang, Guiyang, 550001, China.
Jiajun LiuDepartment of Rheumatology and Immunology, The First People's Hospital Of Guiyang, Guiyang, 550001, China.
Fang TangDepartment of Rheumatology and Immunology, The Second Affiliated Hospital of Guizhou University of Traditional Chinese Medicine, Guiyang, 550002, China. tangfang202210@163.com.
Haixia FanDepartment of Sleep center, First Hospital of Shanxi Medical University, Taiyuan, 030001, China. fhxj251@163.com.

Funding

Guizhou Provincial Basic Research Program(Natural Science) Fundamentals of Qian Kehe-ZK General 436
6 · The paper itself

Abstract

objectiveWe intended to investigate the correlation of the geriatric nutritional risk index (GNRI) and the risks of all-cause and cardiovascular mortality in elderly patients with osteoarthritis (OA).

methodsThis study included 2,922 OA patients aged ≥ 60 years from National Health and Nutrition Examination Survey (NHANES) from 1999 to 2018. GNRI was obtained using serum albumin and body weight, with participants stratified into high (≥ 98) and low (< 98) GNRI groups. Cox regressions, survival analysis, and restricted cubic spline (RCS) regression have been utilized to assess mortality risks. Nonlinear threshold effects were evaluated using piecewise regression. Moreover, subgroup analyses have also been completed based on demographic, lifestyle, and clinical features.

resultsParticipants with low GNRI had significantly higher risks of all-cause mortality (adjusted HR = 1.494, 95% CI: 1.192-1.872, P < 0.001) and cardiovascular mortality (adjusted HR = 1.592, 95% CI: 1.142-2.219, P = 0.006). RCS analysis presented with a nonlinear J-shaped relationship, with optimal GNRI around 120. Subgroup analyses confirmed consistent associations across age, sex, race, and comorbidity strata.

conclusionLower GNRI could independently lead to increased all-cause and cardiovascular mortality in OA patients, highlighting the importance of nutritional assessment in OA management. As a result, GNRI could serve as a valuable prognostic indicator for identifying high-risk individuals who could benefit from targeted nutritional interventions.

Indexed as

Cardiovascular DiseasesGeriatric AssessmentNutritional StatusNutrition AssessmentOsteoarthritisAgedAged, 80 and overCause of DeathFemaleHumansMaleMiddle AgedNutrition SurveysRisk AssessmentRisk FactorsAll-cause and cardiovascular mortalityGeriatric nutritional risk indexNutritionalOsteoarthritisRisk

Identifiers

PMID40764522
PMCPMC12326807

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.