Evidence map›Paper›PMID 40764953›Full record

ArticleBMC public health2025

Long-term impact of the SARS-CoV-2 pandemic on respiratory viruses in Germany.

Ralf Eggeling, Florian König, Lisa Koeppel, Laura-Inés Böhler, Michael Böhm, Norbert Schmeißer, Nico Pfeifer, Rolf Kaiser, Clinical Virology Network

Abstract read
In one paragraph

Article in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ralf EggelingDepartment of Computer Science, University of Tübingen, Tübingen, Germany. ralf.eggeling@uni-tuebingen.de.
Florian KönigDepartment of Computer Science, University of Tübingen, Tübingen, Germany.
Lisa KoeppelDepartment of Infectious Disease and Tropical Medicine, Heidelberg University Hospital, Heidelberg, Germany.
Laura-Inés BöhlerDepartment of Infectious Disease and Tropical Medicine, Heidelberg University Hospital, Heidelberg, Germany.
Michael BöhmInstitute of Virology, Faculty of Medicine and University Hospital Cologne, Köln, Germany.
Norbert SchmeißerMedeora GmbH, Köln, Germany.
Nico PfeiferDepartment of Computer Science, University of Tübingen, Tübingen, Germany.
Rolf KaiserInstitute of Virology, Faculty of Medicine and University Hospital Cologne, Köln, Germany. rolf.kaiser@uk-koeln.de.
Clinical Virology Network

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRespiratory viral diseases are one of the greatest challenges facing our healthcare system, with them being one of the main causes of death. This has been demonstrated once again by the impact of the SARS-CoV-2 pandemic in recent years. We study the impact of the SARS-CoV-2 pandemic on the prevalence of respiratory viruses by analysing a subset of the Clinical Virology network database, covering 2,216,198 samples tested for 18 different viral pathogens in the time span from 2010 to 2024.

methodsWe calculated the prevalence of 17 respiratory viruses before and after onset of the SARS-CoV-2 pandemic and compared the degree of seasonality shift with a newly developed a metric dubbed seasonal disruption index. In addition, we compared coinfection statistics prior to and after the pandemic onset, and also studied the correlation of infection counts with non-pharmaceutical interventions in the time frame from early 2020 to end of 2022.

resultsWe found that the viral pathogens show a varying degree of seasonality disruption. It is largest among those that are known to show a highly seasonal behavior, namely Influenza and RSV, the latter having the highest seasonal disruption index. Most perennial viruses continued to appear throughout the year. Coinfections occurred before and after the pandemic; patterns before and after pandemic onset are surprisingly similar. The occurrence of most viruses is nonlinearly correlated with the degree of non-pharmaceutical interventions.

conclusionThe SARS-CoV-2 pandemic had a considerable impact on the occurrence and seasonality of other respiratory viruses. While nearly all seasonality patterns were initially disrupted due to the heavy non-pharmaceutical interventions, viruses are regaining their pre-pandemic seasonality.

Indexed as

COVID-19Respiratory Tract InfectionsVirus DiseasesCoinfectionGermanyHumansPandemicsPrevalenceSARS-CoV-2SeasonsCoinfectionsCOVID-19Non-pharmaceutical interventionsRespiratory virusesSARS-CoV-2 pandemicSeasonality

Identifiers

PMID40764953
PMCPMC12326739

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.