ArticlePhysical activity and nutrition2025
Influences of short-term hypobaric hypoxia training on body composition, maximal aerobic power, and pro-oxidant/antioxidant balance in healthy young adults: a randomized controlled pilot study.
Article in Physical activity and nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.
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1 citing paper in PubMed, 1 synthesis or guideline pooled it.
- The Effects of Intermittent Hypoxic Training Strategies on Maximal Oxygen Uptake in Healthy Humans: A Meta-analysis with Meta-regression.Sports medicine (Auckland, N.Z.) · 2026Pooled it
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Authors and funding
5 authors.
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No grant is acknowledged in the PubMed record.
Abstract
purposeThis study aimed to investigate the effects of short-term hypobaric hypoxia training on body composition, maximal aerobic power, oxidative stress, and antioxidant capacity in healthy young adults.
methodsFifteen healthy male volunteers were randomly assigned to two groups for 3 weeks, either the normoxia group (n = 8) or hypoxia group (n = 7), and evaluated for three weeks. Hypobaric hypoxia training was performed at an intensity of 60-65%, while heart rate reserve for 60 min, three times per week. Body composition (body weight, body mass index [BMI], body fat percentage, body fat mass, skeletal muscle mass), maximal oxygen uptake (VO2max), serum oxidative stress markers (derivatives of reactive oxygen metabolites [d-ROMs], malondialdehyde [MDA]), and serum antioxidant capacity markers (biological antioxidant potential [BAP], superoxide dismutase [SOD]) were evaluated before and after the three-week intervention.
resultsAmong the body composition variables, weight and BMI significantly decreased in the hypoxia group after training (p <0.05). In addition, VO2max significantly increased in the hypoxic group after training (p <0.05). In contrast, no significant differences were observed in any of the markers related to oxidative stress or antioxidant capacity (p> 0.05).
conclusionThese results suggest that three weeks of hypobaric hypoxia training may reduce body weight and improve VO2max without causing a pro-oxidant/antioxidant imbalance in healthy young adults.
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