Evidence mapPaperPMID 40765144Full record

ArticleBiophysical journal2025

Spatially bound functional heterogeneity drives modular organization in β-cell networks.

Maja Duh, Marko Šterk, Lidija Križančić Bombek, Patrick E MacDonald, Andraž Stožer, Marko Gosak

Abstract read
In one paragraph

Article in Biophysical journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Maja DuhInstitute of Physiology, Faculty of Medicine, University of Maribor, Maribor, Slovenia; Department of Physics, Faculty of Natural Sciences and Mathematics, University of Maribor, Maribor, Slovenia; Alma Mater Europaea University, Maribor, Slovenia.
Marko ŠterkInstitute of Physiology, Faculty of Medicine, University of Maribor, Maribor, Slovenia; Alma Mater Europaea University, Maribor, Slovenia; Institute of Information Science, Maribor, Slovenia.
Lidija Križančić BombekInstitute of Physiology, Faculty of Medicine, University of Maribor, Maribor, Slovenia.
Patrick E MacDonaldDepartment of Pharmacology and Alberta Diabetes Institute, University of Alberta, Edmonton, AB, Canada.
Andraž StožerInstitute of Physiology, Faculty of Medicine, University of Maribor, Maribor, Slovenia. Electronic address: andraz.stozer@um.si.
Marko GosakInstitute of Physiology, Faculty of Medicine, University of Maribor, Maribor, Slovenia; Department of Physics, Faculty of Natural Sciences and Mathematics, University of Maribor, Maribor, Slovenia; Alma Mater Europaea University, Maribor, Slovenia. Electronic address: marko.gosak@um.si.

Funding

Linking islet cell function and identity from in vitro to in situU01DK120447 · NIDDK · UNIVERSITY OF ALBERTA · PI ARROJO E DRIGO, RAFAEL, LUNDBERG, EMMA · 2018 to 2021
$3.0M
NIDDK NIH HHS U01 DK120447
6 · The paper itself

Abstract

Coordinated responses of pancreatic β-cell networks to changes in extracellular nutrient concentrations are a well-established phenomenon with significant implications for insulin secretion. This study investigates the organization and spatiotemporal activity patterns of collective β-cell dynamics and their relationship to functional network structures. Our findings highlight that functional heterogeneity among β-cells is reflected in oscillatory Ca

Indexed as

Insulin-Secreting CellsAnimalsCalciumCalcium SignalingGlucoseHumansMiceCalciumGlucose

Identifiers

PMID40765144
PMCPMC12709238

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.