Evidence map›Paper›PMID 40765178›Full record

Observational studyJournal of pediatric gastroenterology and nutrition2025

Protein intake and insulin-like growth factor-1 at 12 months and associations with growth, body composition, and metabolic syndrome at 8 years.

Gabriella O Seidal, Jovanna Dahlgren, Stefan Bergman, Gerd A Tangen, Josefine Roswall

Abstract readObservational Study
In one paragraph

Observational study in Journal of pediatric gastroenterology and nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Gabriella O SeidalDepartment of Pediatrics, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.ORCID https://orcid.org/0009-0006-7114-6607
Jovanna DahlgrenDepartment of Pediatrics, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Stefan BergmanPrimary Health Care Unit, Department of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Gerd A TangenDepartment of Pediatrics, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Josefine RoswallDepartment of Pediatrics, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

Funding

Region HallandStiftelsen SamaritenVästra Götalandsregionen
6 · The paper itself

Abstract

objectivesMetabolic programming may occur during early life and have long-lasting effects on metabolic health. This study examined what impact early protein intake and levels of insulin-like growth factor (IGF-1) at 1 year of age had on growth, body composition and risk factors for metabolic syndrome at 8 years of age.

methodsThis was a prospective, observational, population-based study of 551 healthy, Swedish children. We used food diaries handed in at 1 year of age, and IGF-1 was measured at the same age. At 8 years of age, the children attended a clinical visit, where they underwent a dual X-ray absorptiometry scan, blood sampling, and anthropometry measurements.

resultsProtein intake at 1 year of age was associated with high waist circumference and insulin resistance measured as homeostatic model assessment for insulin resistance, at 8 years of age.

conclusionsProtein intake at 1 year of age may have an impact on later metabolic health, mainly in form of insulin resistance and waist circumference.

Indexed as

Body CompositionChild DevelopmentDietary ProteinsInsulin-Like Growth Factor IMetabolic SyndromeAbsorptiometry, PhotonChildFemaleHumansInfantInsulin-Like PeptidesInsulin ResistanceMaleProspective StudiesRisk FactorsSwedenDietary ProteinsInsulin-Like Growth Factor IInsulin-Like Peptidesmacro nutrientsmetabolismnutritionobesity

Identifiers

PMID40765178
PMCPMC12484714

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.