Evidence mapPaperPMID 40765373Full record

ReviewJournal of diabetes2025

A Comprehensive Review of Novel Advances in Type 1 Diabetes Mellitus.

Yazdan Ebrahimpour, Sahbasadat Khatami, Mahsa Saffar, Alireza Fereidouni, Zahra Biniaz, Nafiseh Erfanian, Mohammad Fereidouni

Abstract readReview
In one paragraph

Review in Journal of diabetes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. (TCRαβCells · 2025
    Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yazdan EbrahimpourStudent Research Committee, Birjand University of Medical Sciences, Birjand, Iran.ORCID https://orcid.org/0009-0005-7058-7948
Sahbasadat KhatamiStudent Research Committee, Birjand University of Medical Sciences, Birjand, Iran.
Mahsa SaffarStudent Research Committee, Birjand University of Medical Sciences, Birjand, Iran.
Alireza FereidouniCellular and Molecular Research Center, Birjand University of Medical Sciences, Birjand, Iran.
Zahra BiniazStudent Research Committee, Birjand University of Medical Sciences, Birjand, Iran.
Nafiseh ErfanianCellular and Molecular Research Center, Birjand University of Medical Sciences, Birjand, Iran.
Mohammad FereidouniCellular and Molecular Research Center, Birjand University of Medical Sciences, Birjand, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Type 1 diabetes mellitus (T1DM) is a chronic autoimmune disorder where the immune system targets and destroys insulin-producing β-cells in the pancreas. It generally emerges during childhood or adolescence, but individuals of any age can be affected. In contrast to Type 2 diabetes mellitus (T2DM) which is often associated with lifestyle factors, T1DM cannot be prevented and necessitates lifelong management. Currently, there is no definitive cure for T1DM, and patients rely on continuous insulin injections for their entire lives. Ongoing developments in insulin treatment, such as insulin pumps, continuous glucose monitoring, and hybrid closed-loop systems, offer promising alternatives. Despite advancements in intensive glycemic control that have reduced the occurrence of microvascular and macrovascular complications, a significant number of T1DM patients still these issues. Extensive research efforts are crucial to achieve early detection, prevent the loss of β-cells, and devise improved treatment strategies to enhance the quality of life and prognosis for those affected. This review explores the most noteworthy and recent advancements in the field of T1DM.

Indexed as

Diabetes Mellitus, Type 1Blood GlucoseBlood Glucose Self-MonitoringHumansHypoglycemic AgentsInsulinInsulin Infusion SystemsBlood GlucoseHypoglycemic AgentsInsulingene therapyimmunotherapyType 1 diabetes mellitus

Identifiers

PMID40765373
PMCPMC12326085

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.