Evidence map›Paper›PMID 40765665›Full record

ReviewClinics in colon and rectal surgery2025

Segmental versus Extended Resection for Colon Cancer in Lynch Syndrome.

Jared R Hendren, Josh Sommovilla

Abstract readReview
In one paragraph

Review in Clinics in colon and rectal surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jared R HendrenDepartment of Colon and Rectal Surgery, Digestive Disease and Surgery Institute, Cleveland Clinic Foundation, Cleveland, Ohio.
Josh SommovillaDepartment of Colon and Rectal Surgery, Digestive Disease and Surgery Institute, Cleveland Clinic Foundation, Cleveland, Ohio.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lynch's syndrome is a common cause of hereditary colorectal cancer (CRC), resulting in higher risk of CRC and development of subsequent, metachronous CRC (mCRC). Beyond treating the primary cancer, surgeons and patients must decide on whether performing an extended colectomy, to reduce the risk of mCRC, is worth the change in function that comes with the larger operation. Considerations include likelihood for mCRC, morbidity and quality of life after resection, impact of pathogenic variant, and certain other cancer risk reduction options. The contemporary evidence to guide these decisions is reviewed herein.

Indexed as

cancer surveillancecolectomycolon cancerLynch's syndromemismatch repair

Identifiers

PMID40765665
PMCPMC12321363

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.