Evidence map›Paper›PMID 40766281›Full record

ReviewBlood vessels, thrombosis & hemostasis2025

ECMO-induced coagulopathy: strategic initiatives for research and clinical practice (a workshop report of the NHLBI).

Jerrold H Levy, Peta M A Alexander, Alisa S Wolberg, Owen J T McCarty, Anthony E Pusateri, Raquel R Bartz, Wolfgang Bergmeier, Mitchell J Cohen, Jean M Connors, James H Morrissey and 4 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Blood vessels, thrombosis & hemostasis, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Observational
  7. Review
  8. Review
  9. Review
  10. Review
  11. Observational
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Jerrold H LevyDepartment of Anesthesiology, Critical Care, and Surgery (Cardiothoracic), Duke University School of Medicine, Durham, NC.
Peta M A AlexanderDepartment of Cardiology, Boston Children's Hospital and Department of Pediatrics, Harvard Medical School, Boston, MA.
Alisa S WolbergDepartment of Pathology and Laboratory Medicine and University of North Carolina Blood Research Center, University of North Carolina at Chapel Hill, Chapel Hill, NC.
Owen J T McCartyDepartment of Biomedical Engineering, Oregon Health & Science University, Portland, OR.
Anthony E PusateriNaval Medical Research Unit San Antonio, Joint Base San Antonio-Fort Sam Houston, Houston, TX.
Raquel R BartzDepartment of Anesthesia, Wake Forest School of Medicine, Winston Salem, NC.
Wolfgang BergmeierDepartment of Biochemistry and Biophysics and UNC Blood Research Center, University of North Carolina at Chapel Hill, Chapel Hill, NC.
Mitchell J CohenDepartment of Surgery, University of Colorado School of Medicine, Aurora, CO.
Jean M ConnorsHematology Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
James H MorrisseyDepartment of Biological Chemistry, University of Michigan Medical School, Ann Arbor, MI.
Matthew D NealDepartment of Surgery, Trauma and Transfusion Medicine Research Center, University of Pittsburgh, Pittsburgh, PA.
Elisabeth T TracyDepartment of Surgery, UNC Children's, University of North Carolina School of Medicine, Chapel Hill, NC.
Keith McCraeBenign Hematology, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH.
Bruce A SullengerDepartment of Surgery, Duke University School of Medicine, Durham, NC.

Funding

Translating Mechanistic Insights into Intrinsic Xase FunctionP01HL139420 · NHLBI · CHILDREN'S HOSP OF PHILADELPHIA · PI Sriram Krishnaswamy · 2018 to 2026
$22.4M
NHLBI NIH HHS P01 HL139420
6 · The paper itself

Abstract

In May 2024, the Division of Blood Diseases and Resources of the National Heart, Lung, and Blood Institute (NHLBI) hosted a hybrid workshop on "Extracorporeal membrane oxygenation (ECMO)-induced coagulopathy: strategic initiatives for research and clinical practice." The event brought together clinicians, scientists, bioengineers, and policymakers to address the challenges of ECMO-associated coagulopathy and explore novel therapeutic approaches. Through expert presentations and collaborative discussions, the workshop focused on innovative anticoagulation strategies, precision medicine, and advanced diagnostics to enhance patient care. The discussions also identified critical research gaps and opportunities for future interdisciplinary collaboration. This summary reviews the current state of knowledge and outlines future research directions for improving ECMO-induced coagulopathy management.

Identifiers

PMID40766281
PMCPMC12320426

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.