In one paragraphArticle in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from itWhat it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
5 · Who and what moneyAuthors and funding
19 authors.
Mingxue GuDuncan Neurological Research Institute, Texas Children's Hospital, Houston, TX 77030, USA.
Colleen E StrohleinNeuroscience Graduate Program, Baylor College of Medicine, Houston, TX 77030, USA.ORCID 0000-0002-2634-0770 Lindsey D GoodmanDuncan Neurological Research Institute, Texas Children's Hospital, Houston, TX 77030, USA.ORCID 0000-0002-9255-3811 Sasidhar PasupuletiDuncan Neurological Research Institute, Texas Children's Hospital, Houston, TX 77030, USA.
Zahid ShaikDuncan Neurological Research Institute, Texas Children's Hospital, Houston, TX 77030, USA.ORCID 0009-0006-0270-9058 Liwen MaDuncan Neurological Research Institute, Texas Children's Hospital, Houston, TX 77030, USA.
Yarong LiDepartment of Neurology, Baylor College of Medicine, Houston, TX 77030, USA.
Jiayang LiDuncan Neurological Research Institute, Texas Children's Hospital, Houston, TX 77030, USA.
Morgan C StephensDuncan Neurological Research Institute, Texas Children's Hospital, Houston, TX 77030, USA.
Michal TyrlíkDuncan Neurological Research Institute, Texas Children's Hospital, Houston, TX 77030, USA.ORCID 0000-0002-4928-533X Zhandong LiuDuncan Neurological Research Institute, Texas Children's Hospital, Houston, TX 77030, USA.ORCID 0000-0002-7608-0831 Ismael Al-RamahiDuncan Neurological Research Institute, Texas Children's Hospital, Houston, TX 77030, USA.
Juan BotasDuncan Neurological Research Institute, Texas Children's Hospital, Houston, TX 77030, USA.ORCID 0000-0001-5476-5955 Chad A ShawDuncan Neurological Research Institute, Texas Children's Hospital, Houston, TX 77030, USA.ORCID 0000-0001-7267-5398 Oguz KancaDuncan Neurological Research Institute, Texas Children's Hospital, Houston, TX 77030, USA.ORCID 0000-0001-5438-0879 Hugo J BellenDuncan Neurological Research Institute, Texas Children's Hospital, Houston, TX 77030, USA.ORCID 0000-0001-5992-5989 Joshua M ShulmanDepartment of Neurology, Baylor College of Medicine, Houston, TX 77030, USA.
Funding
Medical Scientist Training ProgramT32GM136611 · NIGMS · BAYLOR COLLEGE OF MEDICINE · PI Benjamin J Frankfort, Katherine Yudeh King · 2020 to 2026
$10.0MPreclinical and Clincial OutcomesP50HD103555 · NICHD · BAYLOR COLLEGE OF MEDICINE · PI MIRJANA MALETIC-SAVATIC · 2020 to 2026
$9.9MFunctional Genomic Dissection of Alzheimer's Disease in Humans and Drosophila ModelsU01AG072439 · NIA · BAYLOR COLLEGE OF MEDICINE · PI BELLEN, HUGO J, BOTAS, JUAN · 2021 to 2025
$8.4MSteps towards a paternal gene activation therapy for Angelman syndromeU54HD083092 · NICHD · BAYLOR COLLEGE OF MEDICINE · PI NELSON, DAVID LOREN, NEUL, JEFFREY L · 2014 to 2019
$7.8MDecoding the impact of sex differences on Alzheimer's disease riskR01AG074009 · NIA · BAYLOR COLLEGE OF MEDICINE · PI AL-RAMAHI, ISMAEL, LICHTARGE, OLIVIER · 2021 to 2025
$6.0MA Comprehensive Resource for Manipulating the Drosophila GenomeR24OD031447 · OD · BAYLOR COLLEGE OF MEDICINE · PI HUGO J BELLEN, Oguz Kanca · 2021 to 2026
$5.2MMutidisciplinary Training;Brain Disorders &DevelopmentT32NS043124 · NINDS · BAYLOR COLLEGE OF MEDICINE · PI SWANN, JOHN WILLIAM · 2002 to 2021
$4.6MIMPACTS OF GLIAL LIPID DROPLETS ON OXIDATIVE STRESS AND NEURODEGENERATION IN ALZHEIMER'S DISEASER01AG073260 · NIA · BAYLOR COLLEGE OF MEDICINE · PI BELLEN, HUGO J · 2021 to 2025
$2.6MINVESTIGATING THE ROLE OF THE CYTOSKELETON IN NEURODEGENERATIONF31NS129062 · NINDS · BAYLOR COLLEGE OF MEDICINE · PI STEPHENS, MORGAN CATHERINE · 2022 to 2024
$143kNIA NIH HHS R01 AG073260NIA NIH HHS R01 AG074009NIA NIH HHS U01 AG072439NICHD NIH HHS P50 HD103555NICHD NIH HHS U54 HD083092NIGMS NIH HHS T32 GM136611NIH HHS R24 OD031447NINDS NIH HHS F31 NS129062NINDS NIH HHS T32 NS043124
6 · The paper itselfAbstract
Most Alzheimer's disease (AD) susceptibility genes have poorly understood roles in the central nervous system (CNS). To address this gap, we systematically characterized 100 conserved candidate AD risk genes using a cross-species strategy in the fruit fly,
Indexed as
amyloid-betafunctional genomicsgene expression patternsgenetic screenGWASKozak-GAL4T2A-GAL4tau
Identifiers
PMID40766358
PMCPMC12324250
What Socratic holds
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