Evidence map›Paper›PMID 40766458›Full record

ArticlebioRxiv : the preprint server for biology2025

Development of ENTV reverse genetics system and phenotypic evaluation of rescued virus reveals host-specific replication patterns in mosquitoes.

Marina Fujii, Emily N Gallichotte, Irma Sanchez-Vargas, Brooke M Enney, Lauren E Malsick, Gregory D Ebel, Brian J Geiss

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Marina FujiiDepartment of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, USA.
Emily N GallichotteDepartment of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, USA.ORCID 0000-0002-8937-5583
Irma Sanchez-VargasDepartment of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, USA.ORCID 0000-0002-1724-7005
Brooke M EnneyDepartment of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, USA.
Lauren E MalsickDepartment of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, USA.ORCID 0000-0002-6311-5222
Gregory D EbelDepartment of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, USA.ORCID 0000-0002-4458-9959
Brian J GeissDepartment of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, USA.ORCID 0000-0001-8180-5772

Funding

Quasispecies dynamics in arbovirus persistence emergence and fitnessR01AI067380 · NIAID · UNIVERSITY OF NEW MEXICO · PI Gregory David Ebel · 2007 to 2026
$7.7M
Defining the Translocation Mechanisms of SARS-CoV-2 nsp13 Helicase to Aid in Antiviral DevelopmentR01AI166050 · NIAID · OKLAHOMA STATE UNIVERSITY STILLWATER · PI MCCULLAGH, MARTIN · 2021 to 2025
$2.2M
NIAID NIH HHS R01 AI067380NIAID NIH HHS R01 AI166050
6 · The paper itself

Abstract

Entebbe bat virus (ENTV) is a bat-associated flavivirus with no known vector. Research into the biology of this virus, including assessment of the possibility that it may be vector-transmitted, is hindered by a lack of molecular tools and robust genetic systems. Therefore, we sequenced the complete 3' untranslated region, which was not previously available, and developed an infectious clone of ENTV to facilitate further investigation of the virus. Virus derived from the clone replicated similarly to the parental virus isolate in various vertebrate cells. Surprisingly, ENTV replicated to high titers in

Identifiers

PMID40766458
PMCPMC12324323

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.