Evidence map›Paper›PMID 40766556›Full record

ArticlebioRxiv : the preprint server for biology2025

Modeling simian immunodeficiency virus (SIV) latency in primary rhesus macaque CD4

Lea M Matschke, Matthew R Reynolds

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Lea M MatschkeDepartment of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin, Madison WI.
Matthew R ReynoldsDepartment of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin, Madison WI.ORCID 0000-0002-1484-6408

Funding

WNPRC Supplemental Request for Nonhuman Primate Enclosures to Equip HIV/AIDS-Related Research FacilitiesP51OD011106 · OD · UNIVERSITY OF WISCONSIN-MADISON · PI Dorota A. Grejner-Brzezinska · 2012 to 2026
$150.7M
Determining the impact of ultra-small SIV reservoirs on sustained ART-free remissionR01AI174940 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI Matthew R. Reynolds · 2023 to 2026
$2.7M
NIAID NIH HHS R01 AI174940NIH HHS P51 OD011106
6 · The paper itself

Abstract

Simian immunodeficiency virus (SIV)-infected rhesus macaques are valuable models for HIV cure research, offering insights into tissue reservoirs and testing reservoir-reduction strategies. Despite this utility, low frequencies of latently infected cells

Identifiers

PMID40766556
PMCPMC12324229

What Socratic holds

Textmetadata
LicenceCC BY-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.