ArticlebioRxiv : the preprint server for biology2025
The Crunchometer: A Low-Cost, Open-Source Acoustic Analysis of Feeding Microstructure.
Elvi Gil-Lievana, Benjamin Arroyo, Jesús Pérez-Ortega, Axl Lopez, Luis Alfredo Rodriguez Blanco, Xarenny Diaz, Gustavo Hernandez, Alam Coss, Emily Alway, Naama Reicher and 4 more
Abstract readPreprint
In one paragraphArticle in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
5 · Who and what moneyAuthors and funding
14 authors.
Elvi Gil-LievanaLaboratory Neurobiology of Appetite; Department of Pharmacology, CINVESTAV, 07360, Mexico City, Mexico.
Benjamin ArroyoLaboratory Neurobiology of Appetite; Department of Pharmacology, CINVESTAV, 07360, Mexico City, Mexico.
Jesús Pérez-OrtegaLaboratory Neurobiology of Appetite; Department of Pharmacology, CINVESTAV, 07360, Mexico City, Mexico.ORCID 0000-0001-8502-1692 Axl LopezLaboratory Neurobiology of Appetite; Department of Pharmacology, CINVESTAV, 07360, Mexico City, Mexico.
Luis Alfredo Rodriguez BlancoLaboratory Neurobiology of Appetite; Department of Pharmacology, CINVESTAV, 07360, Mexico City, Mexico.
Xarenny DiazLaboratory Neurobiology of Appetite; Department of Pharmacology, CINVESTAV, 07360, Mexico City, Mexico.
Gustavo HernandezLaboratory Neurobiology of Appetite; Department of Pharmacology, CINVESTAV, 07360, Mexico City, Mexico.
Alam CossLaboratory Neurobiology of Appetite; Department of Pharmacology, CINVESTAV, 07360, Mexico City, Mexico.ORCID 0000-0002-3727-0720 Naama ReicherLaboratory of Gut-Brain Neurobiology, Duke University, Durham, NC 27710; USA.
Enrique Hernández LemusComputational Genomics Division, National Institute of Genomic Medicine (INMEGEN), Mexico City, Mexico.
Ranier GutierrezLaboratory Neurobiology of Appetite; Department of Pharmacology, CINVESTAV, 07360, Mexico City, Mexico.ORCID 0000-0002-9688-0289 Funding
Medical Scientist Training Program Training GrantT32GM145449 · DUKE UNIVERSITY · 2025 to 2025
$1.3MBacteria sensory transduction from gut to brain to modulate behaviorR01DK132070 · DUKE UNIVERSITY · 2025 to 2025
$410kGlutamatergic neurotransmission in gut neuropod cellsR01DK131112 · DUKE UNIVERSITY · 2025 to 2025
$397kEfferent vagal modulation of neuropod cells in the small intestineK01DK131403 · UNIVERSITY OF ARIZONA · 2025 to 2025
$155kF32 - Bitter chemosensation from gut to brainF32DK139628 · DUKE UNIVERSITY · 2025 to 2025
$81kNCCIH NIH HHS R21 AT010818NIDDK NIH HHS F32 DK139628NIDDK NIH HHS K01 DK131403NIDDK NIH HHS R01 DK131112NIDDK NIH HHS R01 DK132070NIDDK NIH HHS R03 DK114500NIGMS NIH HHS T32 GM145449NIMH NIH HHS DP2 MH122402
6 · The paper itselfAbstract
Elucidating the neuronal circuits that govern appetite requires a detailed analysis of the microstructure of solid food consumption. A significant barrier in this field is that existing techniques for monitoring feeding are either prohibitively expensive, limiting their use, or lack the high temporal resolution necessary to align feeding events with neuronal activity. To overcome this, we developed the Crunchometer, a low-cost, open-source acoustic system that uses computational algorithms to create high-resolution feeding ethograms. We validated the system by monitoring feeding across different energy states (hunger/satiety) and by demonstrating that the anti-obesity drug semaglutide suppresses food intake and reduces preference for a high-fat diet. Crucially, the Crunchometer integrates seamlessly with
Identifiers
PMID40766613
PMCPMC12324344
What Socratic holds
Textmetadata
LicenceCC BY-NC
Read underepoch 390