ArticleJournal of the American Heart Association2025
Role of Nighttime Light in the Association Between Air Pollution Exposure and Cardiovascular Disease.
Article in Journal of the American Heart Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- The environmental exposome in heart failure risk and progression.Nature reviews. Cardiology · 2026Review
- Particulate Matter Exposure and Progression Trajectories of Cardiovascular Disease, Mood Disorders, Comorbidity, and Mortality: Associations and Underlying Metabolic Mechanisms.Environmental science & technology · 2025Article
Corrections and comments
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAir pollution is a known contributor to cardiovascular disease (CVD) and CVD death. However, the potential role of nighttime light (NTL) in the relationship between ambient air pollution and CVD risk remains uncertain.
methodsIn this prospective cohort study, we analyzed data from 416 032 participants in the UKB (UK Biobank) to investigate the relationships among air pollution, NTL, and CVD. Air pollution levels were assessed using latent profile analysis to capture joint exposure to multiple types of pollution. Cox proportional hazards regression models were used to estimate the associations between individual and joint exposures to air pollution and CVD. The role of NTL was explored through joint and mediation analyses.
resultsIndividual and joint air pollution levels were significantly associated with increased CVD risk. Specifically, individuals exposed to severe levels of air pollution had higher hazard ratios for coronary heart disease, heart failure, arrhythmia, all-cause CVD death, and stroke: 1.071 (95% CI, 1.022-1.121), 1.318 (95% CI, 1.218-1.427), 1.067 (95% CI, 1.016-1.121), 1.253 (95% CI, 1.117-1.406), and 1.057 (95% CI, 1.005-1.111), respectively. Joint analysis of air pollution and NTL revealed a stepwise increase in CVD risk with increasing exposure levels. Mediation analysis indicated that NTL mediated 24.80% of the effect of air pollution on coronary heart disease and between 20.04% and 39.24% of the effect on heart failure across exposure levels.
conclusionsOur findings indicate positive associations of both air pollution and NTL with CVD, with NTL partially mediating the relationships between air pollution and risks of coronary heart disease and heart failure.
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