ArticleScience translational medicine2025
Regulatory KIR
Registry-linked trialAbstract read
In one paragraph
Article in Science translational medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04978272 (Enhancing Immunity to Malaria in Young Children With Effective Chemoprevention), which is not on this map. Cited by 9 papers.
0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Enhancing Immunity to Malaria in Young Children With Effective Chemoprevention
Who cites it
9 citing papers in PubMed.
- Spatiotemporal single-cell profiling reveals T cell clonal dynamics and phenotypic plasticity in human graft-versus-host disease.Nature immunology · 2026Article
- Regulatory T cell induction strategies and applications in the treatment of immune and non-immune diseases.Signal transduction and targeted therapy · 2026Review
- NK-like and networked CD8bioRxiv : the preprint server for biology · 2026Article
- IL-8-driven neutrophil NETosis triggers endothelial apoptosis and exacerbates preeclampsia.Journal of translational medicine · 2026Article
- Peripheral Regulatory T Cells Display Dynamic Memory Subset Frequency and Inhibitory Marker Expression Across Pregnancy.American journal of reproductive immunology (New York, N.Y. : 1989) · 2026Article
- Donor-derived CD8bioRxiv : the preprint server for biology · 2026Article
- The recent advancements of single-cell RNA sequencing in pre-eclampsia.Frontiers in medicine · 2026Review
- Artemin Serves as a Novel Predictive Biomarker and Exerts a Protective Effect Against Preterm Birth.Journal of inflammation research · 2026Article
- Regulatory KIRNature reviews. Immunology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
23 authors.
Jing LiDepartment of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA.ORCID 0000-0002-9285-9423
Xuerui WangDepartment of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA.ORCID 0000-0001-6448-2676
Andreas I LacknerDepartment of Pathology, School of Medicine, Stanford University, Stanford, CA 94305, USA.ORCID 0000-0002-8034-0181
Purnima NarasimhanDepartment of Obstetrics and Gynecology, School of Medicine, Stanford University, Stanford, CA 94305, USA.
Lin LiDivision of Maternal Fetal Medicine, Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California San Francisco, San Francisco, CA 94158, USA.ORCID 0000-0001-8974-4636
Vamsee MallajosyulaInstitute of Immunity, Transplantation, and Infection, Stanford University School of Medicine, Stanford, CA 94305, USA.ORCID 0000-0002-0658-3652
Mary M JohnsonDepartment of Environmental Health, Harvard T. H. Chan School of Public Health, Boston, MA 02115, USA.
Anna-Lena HöblerDepartment of Obstetrics and Gynecology, Reproductive Biology Unit, Maternal-Fetal Immunology Group, Medical University of Vienna, 1090 Vienna, Austria.ORCID 0000-0001-5529-9378
Adam S KirosinghDepartment of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA 94305, USA.ORCID 0000-0003-0500-9269
Amy E BraunDepartment of Pathology, School of Medicine, Stanford University, Stanford, CA 94305, USA.
Felistas NankyaInfectious Diseases Research Collaboration, Kampala, Uganda.ORCID 0009-0004-6011-9801
Kenneth MusinguziInfectious Diseases Research Collaboration, Kampala, Uganda.
Abel KakuruInfectious Diseases Research Collaboration, Kampala, Uganda.ORCID 0000-0001-9941-1309
Moses KamyaInfectious Diseases Research Collaboration, Kampala, Uganda.ORCID 0000-0001-9106-4234
Philip J RosenthalDepartment of Medicine, University of California San Francisco, San Francisco, CA 94158, USA.ORCID 0000-0002-7953-7622
Grant DorseyDepartment of Medicine, University of California San Francisco, San Francisco, CA 94158, USA.ORCID 0000-0003-0740-0317
Prasanna JagannathanDepartment of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA 94305, USA.ORCID 0000-0001-6305-758X
Michael AngeloDepartment of Pathology, School of Medicine, Stanford University, Stanford, CA 94305, USA.ORCID 0000-0003-1531-5067
Jürgen PollheimerDepartment of Obstetrics and Gynecology, Reproductive Biology Unit, Maternal-Fetal Immunology Group, Medical University of Vienna, 1090 Vienna, Austria.
Stephanie L GawDivision of Maternal Fetal Medicine, Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California San Francisco, San Francisco, CA 94158, USA.ORCID 0000-0003-0891-6964
Virginia D WinnDepartment of Obstetrics and Gynecology, School of Medicine, Stanford University, Stanford, CA 94305, USA.ORCID 0000-0003-1136-2907
Kari C NadeauDepartment of Environmental Health, Harvard T. H. Chan School of Public Health, Boston, MA 02115, USA.ORCID 0000-0002-2146-2955
Mark M DavisInstitute of Immunity, Transplantation, and Infection, Stanford University School of Medicine, Stanford, CA 94305, USA.ORCID 0000-0001-6868-657X
Funding
VECTOR CORE FACILITYP30CA047904 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CHRISTOPHER J. BAKKENIST · 1988 to 2026
$158.0MUniversity of Pittsburgh Clinical and Translational Science InstituteUL1TR001857 · NCATS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E · 2016 to 2025
$129.3MUsing a tonsil organoid system to probe conditions for the induction of protective antibody and T cell responses to influenza.U19AI057229 · NIAID · STANFORD UNIVERSITY · PI Mark Morris Davis · 2003 to 2026
$88.5MPreeclampsia to cardiovascular disease: Life course analysis of biomarkers and riskR01HL139844 · NHLBI · STANFORD UNIVERSITY · PI HLATKY, MARK A., WINN, VIRGINIA D · 2018 to 2021
$9.0MEnhancing immunity to malaria in young children with effective chemopreventionU01AI155325 · NIAID · STANFORD UNIVERSITY · PI JAGANNATHAN, PRASANNA · 2021 to 2025
$6.3MOptimal chemopreventive regimens to prevent malaria and improve birth outcomes in UgandaU01AI141308 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI DORSEY, MATTHEW G, ROSENTHAL, PHILIP JON · 2020 to 2024
$6.0MImmune Tolerance Dysfunction in Pregnancy due to Ambient Air Pollution ExposureR01ES032253 · NIEHS · STANFORD UNIVERSITY · PI NADEAU, KARI C. · 2020 to 2024
$2.2MPlacental malaria: The role of inflammation at the maternal-fetal interfaceK08AI141728 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GAW, STEPHANIE LINA · 2019 to 2023
$950kNCATS NIH HHS UL1 TR001857NCI NIH HHS P30 CA047904NHLBI NIH HHS R01 HL139844NIAID NIH HHS K08 AI141728NIAID NIH HHS U01 AI141308NIAID NIH HHS U01 AI155325NIAID NIH HHS U19 AI057229NIEHS NIH HHS R01 ES032253
Abstract
During pregnancy, immune responses must balance protection from infections with tolerance of the semiallogeneic fetus. However, the mechanisms regulating maternal-fetal tolerance remain poorly understood. Recently, we identified CD8
Indexed as
CD8-Positive T-LymphocytesReceptors, KIRAdultDeciduaFemaleHumansImmune ToleranceMalePregnancyReceptors, KIR
Identifiers
What Socratic holds
Textmetadata
LicenceTDM
Read underepoch 390
Registered trials
NCT04978272ClinicalTrials.gov
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.