Evidence mapPaperPMID 40770633Full record

ArticleBMC health services research2025

Study design of 'PASIBO' - co-creation and development of a physical activity intervention to patients with inflammatory bowel disease.

Tanja Thomsen, Marie Villumsen, Anja Poulsen, Anders B G Hansen, Bente A Esbensen, Tine Jess, Mette Aadahl

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Article in BMC health services research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Tanja ThomsenCenter for Clinical Research and Prevention, Copenhagen University Hospital - Bispebjerg and Frederiksberg, Copenhagen, Denmark. tanja.thomsen@regionh.dk.ORCID http://orcid.org/0000-0002-7112-2318
Marie VillumsenCenter for Clinical Research and Prevention, Copenhagen University Hospital - Bispebjerg and Frederiksberg, Copenhagen, Denmark.ORCID http://orcid.org/0000-0001-8454-4686
Anja PoulsenDepartment of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.ORCID http://orcid.org/0000-0002-0314-3467
Anders B G HansenCenter for Clinical Research and Prevention, Copenhagen University Hospital - Bispebjerg and Frederiksberg, Copenhagen, Denmark.ORCID http://orcid.org/0000-0001-6777-2257
Bente A EsbensenCopenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Centre for Head and Orthopaedics, Rigshospitalet, Copenhagen, Denmark.ORCID http://orcid.org/0000-0001-5331-8221
Tine JessCenter for Molecular Prediction of Inflammatory Bowel Disease (PREDICT), Department of Clinical Medicine, Aalborg University, Copenhagen, Denmark.ORCID http://orcid.org/0000-0002-4391-7332
Mette AadahlCenter for Clinical Research and Prevention, Copenhagen University Hospital - Bispebjerg and Frederiksberg, Copenhagen, Denmark.ORCID http://orcid.org/0000-0001-5904-9747

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPatients with inflammatory bowel disease (IBD) tend to be physically inactive, i.e., not meeting the recommend daily physical activity levels, which may lead to poorer health outcomes and lower quality of life. Despite growing evidence on the benefits of physical activity, few interventions are tailored to the needs and preferences of this population. This study describes the systematic development of a co-created physical activity intervention for patients with IBD.

methodsThe intervention development process was guided by the Medical Research Council (MRC) framework for developing and evaluating complex interventions and informed by principles of co-creation and participatory system-oriented approaches. The process encompassed three stages, including (1) a preparation phase with e.g., literature review, stakeholder consultations and a system mapping workshop, (2) two co-creation workshops with multiple stakeholders to collaboratively design intervention components, and (3) prototyping the intervention, including reviews and feedback from health professionals and other researchers to refine content and delivery model.

resultsStakeholders identified five focus areas as central to the intervention: individualization, community-fostering, mental health, sustainability, and enhancing knowledge about IBD and physical activity. The focus areas were then translated into concrete intervention elements. These included group-based educational sessions and nurse-led individual motivational counselling sessions, supplemented by optional intervention elements, consisting of one-on-one sessions with a physiotherapist, links to short videos featuring physiotherapists demonstrating specific exercises, and peer-support opportunities. During the final stage of the intervention development, feedback from a multidisciplinary team of health professionals and a researcher specializing in physical activity and IBD played a crucial role in refining and finalizing the manual's content and practicality.

conclusionsThe development process resulted in a multicomponent physical activity intervention tailored to the needs and preferences of patients with IBD. The intervention integrates both individual and social components, with some optional. This intervention development highlights the value of combining evidence-based strategies with stakeholder involvement to create a contextually relevant and potentially sustainable physical activity intervention. A feasibility study currently underway will provide further insights into the feasibility and acceptability of the intervention, and the potential need for additional adjustments of intervention elements.

Indexed as

ExerciseInflammatory Bowel DiseasesFemaleHumansProgram DevelopmentQuality of LifeResearch DesignCo-creationHealth promotionInflammatory bowel diseaseIntervention developmentParticipatory researchPhysical activityStakeholder involvement

Identifiers

PMID40770633
PMCPMC12329956

What Socratic holds

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.