ArticleHippocampus2025
Inferior and Middle Longitudinal Fasciculus and Fornix Support Allocentric Representation.
Article in Hippocampus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Hippocampal relational memory and spatial reconstruction: where are we at and where are we bound?Frontiers in cognition · 2026Review
- Inferior and Middle Longitudinal Fasciculus and Fornix Support Allocentric Representation.Hippocampus · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
If a map-like representation in the brain originates within a distributed network of brain regions, then this network should be underpinned by white-matter pathways. To test this, we had 83 young adults learn 15 virtual environments through free exploration, followed by tests of their allocentric and non-allocentric representation of these environments. Diffusion magnetic resonance imaging (dMRI) - based tractography was used to extract the main white matter tracts in the brain, including the inferior and middle longitudinal fasciculus, the main connections between the temporal lobe and the visual cortices, as well as the fornix, the main output pathway from the hippocampus to the cortex. Higher microstructural integrity in the inferior and middle longitudinal fasciculus and fornix, as indexed by higher FA, was associated with a more accurate scale, rotation, and translation-invariant allocentric representation of the objects' positional pattern. These findings show that properties of white matter fiber pathways that link visual cortices to the temporal lobe and the temporal lobe to other parts of the brain underpin a person's ability to form successful map-like representations.
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.