Evidence map›Paper›PMID 40771473›Full record

ArticleFrontiers in medicine2025

The RACOON viral pneumonia score for structured reporting of pre-existing, acute, and post-pneumonic findings on chest CT.

Thorsten Persigehl, Philipp Fervers, Andreas Bucher, Peter Isfort, David Maintz, Tobias Penzkofer, Marwin Sähn, Thomas Vogl, Jonathan Kottlors, Felix Doellinger

Abstract read
In one paragraph

Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Thorsten Persigehl *Institute for Diagnostic and Interventional Radiology, University Hospital Cologne, University of Cologne, Cologne, Germany.
Philipp Fervers *Institute for Diagnostic and Interventional Radiology, University Hospital Cologne, University of Cologne, Cologne, Germany.
Andreas BucherDepartment of Diagnostic and Interventional Radiology, Goethe University Frankfurt, Frankfurt am Main, Germany.
Peter IsfortDepartment of Radiology, University Hospital Aachen, Aachen, Germany.
David MaintzInstitute for Diagnostic and Interventional Radiology, University Hospital Cologne, University of Cologne, Cologne, Germany.
Tobias PenzkoferDepartment of Radiology, Charité - Universitätsmedizin Berlin, Berlin, Germany.
Marwin SähnDepartment of Radiology, University Hospital Aachen, Aachen, Germany.
Thomas VoglDepartment of Diagnostic and Interventional Radiology, Goethe University Frankfurt, Frankfurt am Main, Germany.
Jonathan KottlorsInstitute for Diagnostic and Interventional Radiology, University Hospital Cologne, University of Cologne, Cologne, Germany.
Felix DoellingerDepartment of Radiology, Charité - Universitätsmedizin Berlin, Berlin, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The multi-dimensional RACOON Viral Pneumonia Score (RVPS) was developed to compensate for the main weaknesses of the established one-dimensional chest computed tomography (CT) scores. It aimed to quantify the severity of pneumonia and qualitatively monitor infectious lung disease from the acute stage to post-pneumonic sequelae. Objectives: This research focuses on the original development and evaluation of applicability and inter-reader reliability of the RVPS. Methods: Within the Radiological Cooperative Network (RACOON), the scoring system was developed after several expert meetings and tested in this proof-of-concept study with 8,525 observations. In the subset of inter-reader validation (7,800 observations), eight blinded radiologists applied the RVPS and evaluated the following CT findings for each lung lobe individually: (I) pure ground glass opacities (GGO), (II) GGO and interstitial thickening, (III) consolidations, (IV) linear opacities and reticulations, and (V) fibrotic-like changes. The extent of each pathology was scored on a scale of 0-5 points, and the total involvement was calculated. Inter-reader variability was assessed using Kendall's W. Results: Overall inter-reader reliability of the RVPS was excellent (Kendalls' W 0.95). CT findings associated with acute pneumonia were scored with good agreement (W 0.81-0.87). Moderate uncertainty was introduced when separating category IV vs. category V findings (W 0.55-0.69). The overall extent of post-infectious findings was assessed with good agreement (W 0.79). The longitudinal distribution of subscores allowed for differentiation between acute pneumonia and post-pneumonic sequelae. Conclusion: This study presents the RVPS as a comprehensive tool for inter-reader reliable evaluation, longitudinal monitoring, and structured documentation of the extent as well as quality of chest CT findings in infectious lung disease.

Indexed as

computed tomographyCOVID-19pandemic preparednesspneumoniastructured reporting

Identifiers

PMID40771473
PMCPMC12325055

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.