SynthesisFrontiers in psychiatry2025
Challenges in amphetamine medication availability for individuals with ADHD: a narrative review of the current state of evidence.
Synthesis in Frontiers in psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Innovative Nanomaterial-Based Approaches for the Recognition of Amphetamine in Attention Deficit Hyperactivity Disorder Management.Analytical science advances · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Attention-deficit/hyperactivity disorder (ADHD) is a prevalent neurodevelopmental disorder affecting individuals across various age groups. Access to amphetamine (AMPH) stimulant is a critical component of evidence-based care for individuals with ADHD. In Saudi Arabia, despite clinical guidelines endorsing their use, the availability of AMPH-based stimulants remains limited. Objective: This narrative review aims to explore the current regulatory and policy environment influencing AMPH medication availability for individuals diagnosed with ADHD in Saudi Arabia. Methods: A narrative review methodology was adopted following the Scale for the Assessment of Narrative Review Articles guidelines. A literature search was conducted in PubMed, EBSCO, and PsycINFO using defined search terms related to ADHD, psychostimulants, and Saudi Arabia. Additional grey literature from key regulatory bodies, such as the Saudi Food and Drug Authority (SFDA), the Ministry of Health (MOH), and the Saudi ADHD Society, was also reviewed. Thirteen articles and reports met the eligibility criteria and were included for qualitative synthesis. Results: Methylphenidate is the predominant stimulant prescribed for ADHD, while AMPH-based medications, such as lisdexamfetamine, are under prescribed due to regulatory restrictions, limited formulary inclusion, and supply inconsistencies. Policy reports from national institutions highlight persistent barriers to AMPH access, despite their inclusion in recent clinical practice guidelines. Prescription trends suggest significant treatment gaps for AMPH stimulants. Conclusion: The available evidence suggests a likely shortfall in AMPH-based medications. in Saudi Arabia, despite global and local evidence supporting their efficacy. Our findings suggest the need for enhancing regulatory pathways regarding AMPH access and availability, which requires policy interventions targeting regulatory reform, formulary expansion, and improved awareness among AMPH prescribers.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.