Evidence map›Paper›PMID 40772020›Full record

ArticleFood science & nutrition2025

Shortening Leukocyte Telomere Length Associated With Elevated Blood Diabetes-Related Cardiovascular Risk Factor in Thai Adolescents.

Phennapha Luealai, Tippawan Pongcharoen, Nattira On-Nom, Uthaiwan Suttisansanee, Piya Temviriyanukul, Wantanee Kriengsinyos, Chanakan Khemthong, Chaowanee Chupeerach

Abstract read
In one paragraph

Article in Food science & nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Phennapha LuealaiInstitute of Nutrition, Mahidol University Nakhon Pathom Thailand.
Tippawan PongcharoenInstitute of Nutrition, Mahidol University Nakhon Pathom Thailand.
Nattira On-NomInstitute of Nutrition, Mahidol University Nakhon Pathom Thailand.
Uthaiwan SuttisansaneeInstitute of Nutrition, Mahidol University Nakhon Pathom Thailand.
Piya TemviriyanukulInstitute of Nutrition, Mahidol University Nakhon Pathom Thailand.ORCID https://orcid.org/0000-0002-7590-7024
Wantanee KriengsinyosInstitute of Nutrition, Mahidol University Nakhon Pathom Thailand.
Chanakan KhemthongInstitute of Nutrition, Mahidol University Nakhon Pathom Thailand.
Chaowanee ChupeerachInstitute of Nutrition, Mahidol University Nakhon Pathom Thailand.ORCID https://orcid.org/0000-0002-1093-1621

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Leukocyte telomere length (LTL) is considered a reliable biological indicator of aging. LTL shortening has been associated with an increased risk of cardiometabolic markers among adults. However, evidence for an association in adolescents is limited. This cross-sectional study examined the association between blood biomarkers of cardiovascular diseases and leukocyte telomere length in 59 Thai adolescents with mean age 15 years. Blood samples and anthropometric, clinical, and biochemical data were collected, with relative telomere length (RTL) measured using the quantitative polymerase chain reaction (qPCR) method. Results showed that RTL was negatively associated with Hemoglobin A1C (HbA1C) but positively associated with high density lipoprotein cholesterol (HDL-C). Inflammatory Tumor necrosis factor alpha (TNF-α) was positively correlated with RTL, with a strong association in female adolescents. After adjusting the confounding factors including age, gender, and body mass index (BMI) for age the multivariable models indicated that predictors of shortening RTL were higher levels of HbA1C (

Indexed as

biochemical assessmentinflammatory markermetabolic syndrometeenager health

Identifiers

PMID40772020
PMCPMC12325094

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.