ArticleCureus2025
Effect of Ozempic on Diabetic Nephropathy: A Case Report.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Semaglutide (Ozempic), a Glucagon-like peptide-1 (GLP-1) receptor agonist, has shown promise in improving glycemic control and offering renal protection in type 2 diabetes. We present the case of a 40-year-old male with poorly controlled type 2 diabetes and early diabetic nephropathy, who experienced significant metabolic and renal improvements following semaglutide therapy. Initially, on SGLT2 inhibitors, the patient discontinued treatment due to recurrent urinary tract infections. On presentation, he exhibited hyperglycemia, dyslipidemia, proteinuria, and reduced eGFR. Semaglutide was initiated alongside metformin, gliclazide, antihypertensives, and lipid-lowering agents. Over 12 months, HbA1c improved from 9.8% to 6.1%, and urine albumin-to-creatinine ratio decreased from 267 mg/g to 34 mg/g, with improved eGFR. This case supports the renoprotective and metabolic benefits of semaglutide and highlights its potential as a therapeutic option in patients intolerant to SGLT2 inhibitors.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.