Evidence map›Paper›PMID 40772440›Full record

ArticlePsychological medicine2025

Unraveling the phenotypic expression of ADHD symptoms in middle- and older-aged adults: insights from confirmatory factor analysis of the US Health and Retirement Study.

Stephen Z Levine, Anat Rotstein, Abraham Reichenberg, Robert B Wallace

Abstract read
In one paragraph

Article in Psychological medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Stephen Z LevineSchool of Public Health, https://ror.org/02f009v59University of Haifa, Haifa, Israel.ORCID 0000-0002-5544-0420
Anat RotsteinDepartment of Gerontology, https://ror.org/02f009v59University of Haifa, Haifa, Israel.
Abraham ReichenbergDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Robert B WallaceDepartment of Epidemiology, University of Iowa, Iowa City, IA, USA.

Funding

HRS Yrs29-34: Y33 SSA CoFundingU01AG009740 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Jessica Faul, KENNETH M LANGA · 1990 to 2026
$555.8M
Pulmonary Toxicology Facility CoreP30ES005605 · NIEHS · UNIVERSITY OF IOWA · PI Jong Sung Kim · 1990 to 2026
$40.5M
NIA NIH HHS U01 AG009740NIEHS NIH HHS P30 ES005605
6 · The paper itself

Abstract

backgroundFew studies have examined attention-deficit/hyperactivity disorder (ADHD) symptoms in middle- and older-aged adults. We aim to examine the phenotypic expression of ADHD symptoms in these age groups.

methodsThis study comprised a random sample (

resultsIn the primary analysis, 10 competing confirmatory factor analytic models of ADHD symptoms in middle- and older-aged adults were compared. The best-fitting model was hierarchical with a general ADHD factor at the apex and underneath symptom factors of inattention, hyperactivity, and impulsivity (

conclusionsThese results imply a hierarchical representation of ADHD symptoms in middle- and older-aged adults consisting of a general factor at the apex with neurocognitive and genetic correlates and underneath symptom factors of inattention, hyperactivity, and impulsivity. Collectively, this model offers a novel framework to study the mechanisms of ADHD symptoms in middle- and older-aged adults and points to treatment targets.

Indexed as

AgingAttention Deficit Disorder with HyperactivityAgedAged, 80 and overFactor Analysis, StatisticalFemaleHumansImpulsive BehaviorMaleMiddle AgedPhenotypeUnited StatesADHDadultepidemiologyfactor analysisnational survey

Identifiers

PMID40772440
PMCPMC12360687

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.