ArticleAlzheimer's & dementia : the journal of the Alzheimer's Association2025
Reproductive health history and later life cognition in African Caribbean women.
Article in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Biological and social reproductive factors and late-life cognitive function in middle-aged and older Chinese women.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- Reproductive health history and later life cognition in African Caribbean women.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
introductionDementia prevalence is higher in women, in particular those of African ancestry. Reproductive health may influence dementia risk, yet data from the Caribbean are lacking. We assessed the association of reproductive health with cognition in the Tobago Women's Health Study.
methodsThis population-based study recruited middle to older aged women from the Caribbean Island of Tobago. Cognitive performance was assessed using the Digit Symbol Substitution Test (DSST). Seven indicators of reproductive health were collected via interviews. Multivariable regression models estimated the association between reproductive indicators and DSST score.
resultsAmong 776 women (mean age 55.8 ± 8.9 years), the mean number of live births was 2.83 ± 2.4, and 22% experienced at least one pregnancy complication. Later age at first live birth (mean age 22.7 ± 5.4 years) was significantly associated with higher DSST score (β = 0.35, p < 0.001), independent of other reproductive factors. DISCUSSION: Older age at the time of first live birth appears protective for cognitive function among African Caribbean women. HIGHLIGHTS: Later age at first birth is linked to better cognitive function, independent of other reproductive, demographic, and health factors. This study provides novel insights into cognitive aging among African Caribbean women, an understudied population, addressing a critical gap in research on reproductive history and cognition. This study highlights the need for further research on the longitudinal association between reproductive history and cognition, particularly in African Caribbean women.
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