Evidence map›Paper›PMID 40773070›Full record

ArticleInternational ophthalmology2025

Gonioscopy-assisted transluminal trabeculotomy for intractable ocular hypertension after repeated intravitreal dexamethasone implant injections.

Rukiye Kilic Ucgul, Ahmet Ozan Olgun, Zeynep Beyza Akdeniz, Pınar Inan, Zeynep Aktas, Ahmet Yucel Ucgul

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Article in International ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Rukiye Kilic UcgulDepartment of Ophthalmology, Kırşehir Training and Research Hospital, Ahi Evran University, Kırşehir, Turkey.
Ahmet Ozan OlgunDepartment of Ophthalmology, Kırşehir Training and Research Hospital, Ahi Evran University, Kırşehir, Turkey.
Zeynep Beyza AkdenizDepartment of Ophthalmology, Kırşehir Training and Research Hospital, Ahi Evran University, Kırşehir, Turkey.
Pınar InanDepartment of Ophthalmology, Kırşehir Training and Research Hospital, Ahi Evran University, Kırşehir, Turkey.
Zeynep AktasDepartment of Ophthalmology, University of Texas Health Science Center, San Antonio, TX, USA.
Ahmet Yucel UcgulDepartment of Ophthalmology, Kırşehir Training and Research Hospital, Ahi Evran University, Kırşehir, Turkey. ahmet.yucel.ucgul@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the efficacy and safety of gonioscopy-assisted transluminal trabeculotomy (GATT) in managing intractable ocular hypertension (OHT) following repeated intravitreal dexamethasone implant (DI) injections.

methodsThis retrospective study included patients with steroid-induced OHT unresponsive to maximum tolerated medical therapy who underwent GATT. Primary outcome measures were intraocular pressure (IOP) reduction and surgical success (qualified and complete), number of DI injections.

resultsFourteen eyes of 14 patients (mean age: 66.2 ± 8.3 years) with steroid-induced OHT following repeated DI injections were analyzed. The mean number of DI injections before surgery was 4.2 ± 1.1 over a median period of 18.4 months (range: 12-36 months). The mean preoperative IOP was 33.6 ± 4.1 mmHg, which significantly decreased to 13.5 ± 2.9 mmHg at the first postoperative month (59.8% reduction, p < 0.001) and remained stable at 14.2 ± 3.1 mmHg at final visit. Qualified success was achieved in 100% of cases, while complete success was 71.4%. The mean number of glaucoma medications decreased from 3.1 ± 0.4 preoperatively to 0.4 ± 0.8 postoperatively.

conclusionGATT is a highly effective surgical option for treating intractable steroid-induced OHT following repeated DI injections, achieving significant and sustained IOP reduction while minimizing medication dependence.

Indexed as

DexamethasoneGonioscopyIntraocular PressureOcular HypertensionTrabeculectomyAgedDrug ImplantsFemaleFollow-Up StudiesGlucocorticoidsHumansIntravitreal InjectionsMaleMiddle AgedRetrospective StudiesTreatment OutcomeDexamethasoneDrug ImplantsGlucocorticoidsDexamethasone implant (Ozurdex)Gonioscopy-assisted transluminal trabeculotomy (GATT)Steroid-induced ocular hypertension

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.