ArticleDiabetes research and clinical practice2025
Regional and systemic adipose mass and peripheral conduit artery function.
Article in Diabetes research and clinical practice, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Sport-specific adaptations in body composition and vascular function: a comparative study of swimmers, tennis players, and wrestlers.Frontiers in sports and active living · 2026Article
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Authors and funding
11 authors.
Funding
Abstract
introductionVascular function and metabolic function are inherently coupled. While prior studies have linked body mass index (BMI) and visceral adiposity to reduced FMD, the relationship between whole-body and limb-specific adiposity and vascular function in adults with pre-diabetic levels of insulin resistance remains unclear.
methodsWe assessed body composition (DEXA), insulin resistance (HOMA-IR and Matsuda Index), and brachial artery FMD in 93 pre-diabetic individuals (69 % Female) aged 18-65 with obesity (BMI ≥ 30 kg/m
resultsFMD was not associated with BMI (r = 0.12, p = 0.24), total body fat (kg) (r = -0.12, p = 0.31), or arm fat (kg) (r = 0.00, p = 0.99). In contrast, there was an inverse correlation between FMD and Waist:Hip ratio (r = -0.24, p = 0.03), total body lean mass (r = -0.32, p = 0.005) and arm lean mass (r = -0.25, p < 0.03). The correlation between FMD and Waist:Hip ratio persisted after adjusting for HOMA-IR (r = - 0.31, P = 0.01), the Matsuda Index (r = - 0.31, P < 0.01) and sex (r = -0.35, p = 0.006).
conclusionIn adults with obesity and insulin resistance, higher visceral adiposity, but not systemic and regional fat mass, is independently associated with impaired vascular function. These findings suggest that visceral fat distribution may have detrimental effects on vascular health, distinct from its impact on insulin sensitivity.
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