Evidence map›Paper›PMID 40775400›Full record

ArticleScientific reports2025

Beta cyclodextrin stabilized cupric oxide nanoparticles assisted thermal therapy for lung tumor and its effective in vitro anticancer activity.

Anakha D Rajeeve, Vyshnavi T Veetil, Sabarinathan Palaniyappan, Ramasamy Yamuna, Vishal Bhalla

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Anakha D RajeeveDepartment of Chemistry, Amrita School of Physical Sciences Coimbatore, Amrita Vishwa Vidyapeetham, Coimbatore, India.
Vyshnavi T VeetilDepartment of Chemistry, Amrita School of Physical Sciences Coimbatore, Amrita Vishwa Vidyapeetham, Coimbatore, India.
Sabarinathan PalaniyappanCenter for Biosystems and Machines, King Fahd University of Petroleum and Minerals, Dhahran, Saudi Arabia.
Ramasamy YamunaDepartment of Chemistry, Amrita School of Physical Sciences Coimbatore, Amrita Vishwa Vidyapeetham, Coimbatore, India. r_yamuna@cb.amrita.edu.
Vishal BhallaSchool of Energy and Environment, NICMAR University, Pune, Maharashtra, India. vishal.bhalla@pune.nicmar.ac.in.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The unique physicochemical properties of cupric oxide nanoparticles (CuO NPs) make them suitable for a wide range of therapeutic applications. Here, we synthesized β-cyclodextrin (βCD) capped CuO NPs (CuONPs@βCD) using a simple reduction process. The formation and physicochemical characteristics were identified via different spectroscopic techniques. The CuONPs@βCD displayed antimicrobial activity as good as commercial drugs. Dimethyl thiazolyl tetrazolium bromide (MTT) assay was carried out to assess the anticancer properties of CuONPs@βCD against A549 lung cancer cells. The result demonstrated that the anticancer activity of CuONPs@βCD with IC

Indexed as

Antineoplastic Agentsbeta-CyclodextrinsCopperHyperthermia, InducedLung NeoplasmsMetal NanoparticlesNanoparticlesA549 CellsApoptosisHumansMembrane Potential, MitochondrialReactive Oxygen SpeciesAntineoplastic Agentsbeta-CyclodextrinsbetadexCoppercupric oxideReactive Oxygen SpeciesAnticancerAntimicrobialCOMSOL multiphysicsCuONPs@βCDLung cancerTemperature distribution

Identifiers

PMID40775400
PMCPMC12332176

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.