Evidence map›Paper›PMID 40775555›Full record

ReviewAAPS PharmSciTech2025

An Updated Perspective on Skin Disease Therapy: From Conventional Methods to Nanocarrier Innovations.

Riya Shivgotra, Bindu Soni, Parminder Kaur, Anshuka Sharma, Varun Singh, Nitin Partap, Hossamaldeen Bakrey, Subheet Kumar Jain

Abstract readReview
PubMed Publisher
In one paragraph

Review in AAPS PharmSciTech, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Polymeric Nanogels for Skin Applications.Gels (Basel, Switzerland) · 2026
    Review
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Riya ShivgotraDepartment of Pharmaceutical Sciences, Guru Nanak Dev University, Amritsar, Punjab, 143005, India.ORCID http://orcid.org/0009-0001-1753-1647
Bindu SoniDepartment of Pharmaceutical Sciences, Guru Nanak Dev University, Amritsar, Punjab, 143005, India.ORCID http://orcid.org/0009-0005-9090-9668
Parminder KaurDepartment of Pharmaceutical Sciences, Guru Nanak Dev University, Amritsar, Punjab, 143005, India.ORCID http://orcid.org/0009-0001-5089-3201
Anshuka SharmaDepartment of Pharmaceutical Sciences, Guru Nanak Dev University, Amritsar, Punjab, 143005, India.ORCID http://orcid.org/0009-0004-5000-7304
Varun SinghDepartment of Pharmaceutical Sciences, Guru Nanak Dev University, Amritsar, Punjab, 143005, India.ORCID http://orcid.org/0009-0005-0916-4399
Nitin PartapDepartment of Pharmaceutical Sciences, Guru Nanak Dev University, Amritsar, Punjab, 143005, India.ORCID http://orcid.org/0009-0009-3316-9279
Hossamaldeen BakreyDepartment of Pharmaceutical Sciences, Guru Nanak Dev University, Amritsar, Punjab, 143005, India.ORCID http://orcid.org/0009-0002-6298-4992
Subheet Kumar JainDepartment of Pharmaceutical Sciences, Guru Nanak Dev University, Amritsar, Punjab, 143005, India. subheetjain@rediffmail.com.ORCID http://orcid.org/0000-0003-2272-941X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Skin conditions are becoming more prevalent these days, affecting millions of people daily. Skin disorders include a wide range of conditions that can be benign or even fatal. Several pathogenic infections or inflammatory conditions have historically been the primary causes of skin diseases, causing major challenges. As demonstrated by studies, dermatological conditions are extremely severe, commonly impacting people of all ages and regions, but especially in developing nations, and imposing a heavy social and psychological burden. Conventional topical treatments for several skin diseases suffer from inefficacy, prolonged treatment duration, recurrence, and systemic side effects due to poor drug delivery. The skin's fundamental resistance to drug penetration also poses a significant hurdle. Nanocarriers are one of the most promising approaches since they address the drawbacks of conventional formulations and offer effective drug delivery via the skin. By using nanocarriers to provide continuous release and maintain a localized effect, many diseases or skin conditions can be effectively treated. This review discusses various common skin diseases, challenges associated with conventional treatments, and the impact of nanomedicine on dermatological care. Discussing the role of interleukins, this review also modulates the immune responses implicated in several skin diseases, including psoriasis and atopic dermatitis.

Indexed as

Dermatologic AgentsDrug CarriersNanoparticlesSkin DiseasesAdministration, CutaneousAnimalsDrug Delivery SystemsHumansNanomedicineSkinSkin AbsorptionDermatologic AgentsDrug Carriersgene therapyimmune responsesnovel drug delivery systemsskin diseasestopical therapy

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.