Evidence map›Paper›PMID 40775655›Full record

ArticleTrials2025

Effects of animal-assisted therapy on dental anxiety, behavior, and perceptions in young pediatric patients: a blinded randomized controlled trial.

Grace Kapov, Kasey Linton, Christopher Gatewood, Chuwen Liu, Timothy Strauman, Eric Hodges, Christina Graves, Caroline Sawicki, Di Wu, Kimon Divaris and 1 more

2 registry-linked trialsAbstract readClinical Trial Protocol
In one paragraph

Article in Trials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05464888 narecruitingnot on this map

Animal Assisted Therapy's Effects on Young Dental Patients

TypeinterventionalSponsorUniversity of North Carolina, Chapel HillRan2023 to 2028Enrolled225ConditionsAnxietyArms+Short AAT, +Long AAT, Active control, NO dog
NCT07448714 nacompletednot on this map

Animal Assisted Therapy as a Behavioral Management Technique During Dental Treatment in Pediatric Patients

TypeinterventionalSponsorUniversity of Puerto RicoRan2023 to 2024Enrolled20ConditionsDental Fear and Anxiety, Animal Assisted Therapy, Dental TreatmentArmsanimal assisted therapy
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Dog-assisted therapy in paediatric dentistry: physiological, psychological, and family-centred benefits in managing child dental anxiety.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Grace KapovDepartment of Orthodontics, Adams School of Dentistry, University of North Carolina, 270 Brauer Hall, CB #270, Chapel Hill, NC, 25799, USA.
Kasey LintonDepartment of Orthodontics, Adams School of Dentistry, University of North Carolina, 270 Brauer Hall, CB #270, Chapel Hill, NC, 25799, USA.
Christopher GatewoodAdvanced Dental Associates, Inc., 11312 US 15-501 North, Suite 107-139, Chapel Hill, NC, 27517, USA.
Chuwen LiuDepartment of Biomedical Sciences, Adams School of Dentistry, University of North Carolina, CB #7455, Chapel Hill, NC, 27599, USA.
Timothy StraumanDepartment of Psychology and Neuroscience, Duke University Trinity College of Arts and Sciences, Box 90086, Durham, NC, 27708, USA.
Eric HodgesUNC School of Nursing, University of North Carolina, 5016 Carrington Hall, Chapel Hill, NC, 27599, USA.
Christina GravesDepartment of Biomedical Sciences, Adams School of Dentistry, University of North Carolina, CB #7455, Chapel Hill, NC, 27599, USA.
Caroline SawickiDepartment of Pediatric Dentistry and Dental Public Health, Adams School of Dentistry, University of North Carolina, 228 Brauer Hall, CB #4750, Chapel Hill, NC, 27599, USA.
Di WuDepartment of Biomedical Sciences, Adams School of Dentistry, University of North Carolina, CB #7455, Chapel Hill, NC, 27599, USA.
Kimon DivarisDepartment of Pediatric Dentistry and Dental Public Health, Adams School of Dentistry, University of North Carolina, 228 Brauer Hall, CB #4750, Chapel Hill, NC, 27599, USA.
Laura Anne JacoxDepartment of Orthodontics, Adams School of Dentistry, University of North Carolina, 270 Brauer Hall, CB #270, Chapel Hill, NC, 25799, USA. ljacox@live.unc.edu.

Funding

Re-Entry Supplement: Investigation of Oral Microbial Enzymes for the Detection and Treatment of Periodontal DiseaseUL1TR002489 · NCATS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BUSE, JOHN BERNARD, SHAHEEN, NICHOLAS J · 2018 to 2022
$48.6M
North Carolina Translational and Clinical Sciences Institute (NC TraCS)UM1TR004406 · NCATS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI NICHOLAS J SHAHEEN · 2023 to 2026
$37.5M
Orthognathic speech pathology: Understanding how jaw disharmonies and their surgical correction influence speechK08DE030235 · NIDCR · UNIV OF NORTH CAROLINA CHAPEL HILL · PI JACOX, LAURA ANNE · 2021 to 2025
$889k
Evaluating the Effects of Animal Therapy on Anxiety in Pediatric Dental PatientsR03DE032768 · NIDCR · UNIV OF NORTH CAROLINA CHAPEL HILL · PI JACOX, LAURA ANNE · 2023 to 2024
$308k
NCATS NIH HHS UL1 TR002489NCATS NIH HHS UL1TR002489NCATS NIH HHS UM1 TR004406NIDCR NIH HHS K08DE030235NIDCR NIH HHS R03DE032768
6 · The paper itself

Abstract

backgroundBetween 6 and 22% of children are affected by dental anxiety. Dental anxiety is a significant barrier to dental care and is associated with dental avoidance and negative oral health outcomes. Pharmacological methods of anxiety management are costly, carry risks of adverse outcomes, and may not be acceptable to some families. Alternative non-pharmacological methods are needed for the safe and effective delivery of dental care. Although there is an abundance of literature regarding animal-assisted therapy (AAT) in medicine, only preliminary studies on AAT exist in dentistry. To identify optimal outcome measures for evaluating AAT in pediatric dental contexts, a randomized controlled trial protocol was developed.

methodsA prospective randomized controlled trial protocol was developed to examine the impact of AAT on objective (heart rate, salivary stress and pain markers, and observational coding) and subjective self-reported measures of anxiety, pain, and dental expectations in pediatric patients. The study is designed to enroll 180 pediatric patients (4-8 years old), randomized into three arms (n = 60 per arm) with stratification by age (< 6.5 vs ≥ 6.5) and gender (block size = 4). Two therapy protocols (+ Short AAT and + Long AAT exposures) will be compared relative to an active control (coloring a dog picture) during a diagnostic dental visit consisting of an oral exam, dental cleaning, and simulated bitewing intraoral radiographs. DISCUSSION: This study will provide information on optimal outcome measures to evaluate the impact of AAT on dental anxiety and behavior in pediatric dental patients. Determining the effects of AAT in pediatric dental care may provide a safe, non-pharmacological method of anxiety and behavior management, with broad translational impact.

trial registrationThis trial was registered on ClinicalTrials.gov with number NCT05464888, on 15 July 2022 (first submitted to ClinicalTrials.gov) and 19 July 2022 (first posted to ClinicalTrials.gov).

Indexed as

Animal Assisted TherapyChild BehaviorDental AnxietyDental Care for ChildrenAge FactorsAnimalsChildChild, PreschoolFemaleHeart RateHumansMalePain MeasurementPerceptionProspective StudiesRandomized Controlled Trials as TopicAnimal-assisted therapyAnimal therapyBehavior managementDental anxietyDental fearDentistryDogPediatric dentistry

Identifiers

PMID40775655
PMCPMC12330074

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.