ArticleBMC geriatrics2025
Female predominance in nocturnal hypoxemia among elderly OSAS patients: hemoglobin mediates sex-specific hypoxic burden in Chinese cohorts.
Article in BMC geriatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- The effect of gender on clinical characteristics and diagnostic process of obstructive sleep apnea syndrome.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026Article
- Age and Sex Matter: Phenotypic Heterogeneity, Diagnostic Gaps, and Screening Tool Performance in Obstructive Sleep Apnea-A 10-Year Sleep Clinic Cohort Study.Diagnostics (Basel, Switzerland) · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo explore the clinical characteristics and sex differences in relevant indicators of obstructive sleep apnea syndrome (OSAS) in elderly patients.
methodsA total of 1290 elderly patients diagnosed with OSAS by polysomnography (PSG) from 2015 to 2017 were consecutively collected from multiple medical institutions. Detailed demographic data, laboratory indicators, and sleep breathing parameters were recorded for each patient. All subjects were grouped according to sex, and the differences in each index between groups were statistically analyzed. Furthermore, analyses of the interaction between the influencing factors of nocturnal hypoxia were performed.
resultsThe male to female ratio was 1.62:1 in all subjects. There was no significant difference in age between groups (65 years vs. 66 years). The men had a higher BMI than the women (26.7 kg/m2 vs. 25.8 kg/m2), but the women had a slightly higher ratio of waistline to height (0.56 vs. 0.53). Hemoglobin, creatinine, and uric acid levels were higher in male patients (all P < 0.001). The prevalence of hypertension was higher in both sexes, but it was greater in men (60.4% vs. 67.4%, P = 0.011). Male patients had a greater apnea-hypopnea index (AHI) (25.5 events/h vs. 30.9 events/h) and a longer apnea time (44 s vs. 56 s); nonetheless, the percent of total time with an oxygen saturation lower than 90% during sleep (T90) showed no significant difference between the two groups (3.9% vs. 3.6%, P > 0.05). Furthermore, in men, hemoglobin attenuated the effect of apnea duration on the risk of more pronounced nocturnal hypoxemia (Pinteraction=0.037). In the subgroup of patients ≥ 70 years, the AHI was consistent in both groups, but T90 was longer in women than in men (7.4% vs. 3.8%, P = 0.001).
conclusionsThe proportion of severe OSAS in elderly patients was high. It was more severe in men than in women, but women tended to have more pronounced nighttime hypoxia. Therefore, clinical attention should be paid to sex differences in the effects of hypoxia on health in patients with OSAS.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.