Evidence map›Paper›PMID 40775775›Full record

ReviewHead & face medicine2025

The effects of mitochondrial damage and energy metabolism disorders on the progression of noise-induced deafness and its treatment.

LuHua Xu, HongYan Jiang

Abstract readReview
In one paragraph

Review in Head & face medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

LuHua XuDepartment of Otolaryngology-Head and Neck Surgery, Hainan Medical University Hainan Hospital, Haikou, 570311, China.
HongYan JiangDepartment of Otolaryngology-Head and Neck Surgery, Hainan Medical University Hainan Hospital, Haikou, 570311, China. hyjiangus@163.com.

Funding

Major Science and Technology Projects of Hainan Province ZDKJ2021040Natural Science Foundation of Hainan Province 823RC558
6 · The paper itself

Abstract

Noise-induced hearing loss (NIHL) is a major cause of hearing impairment globally, affecting numerous individuals. The pathogenesis of NIHL is complex, involving multiple mechanisms such as mechanical damage, oxidative stress, mitochondrial dysfunction, and energy metabolism disorders. Although these mechanisms are implicated, the complete understanding of NIHL's pathogenesis remains elusive. In recent years, the role of mitochondrial dysfunction and energy metabolism disorders in NIHL has garnered significant attention. This review aims to provide a comprehensive summary of the pathological mechanisms underlying NIHL, focusing on the contributions of mitochondrial damage and energy metabolism disorders. Moreover, this review evaluates existing therapeutic approaches and proposes future research directions through critical analysis of published evidence.

Indexed as

Energy MetabolismHearing Loss, Noise-InducedMitochondriaMitochondrial DiseasesDisease ProgressionHumansOxidative StressEnergy metabolism disorderMechanismMitochondrial damageNoise-induced hearing lossResearch progressTreatment

Identifiers

PMID40775775
PMCPMC12329933

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.